The Narrow Proton Beam Therapy Unit at the Svedberg Laboratory in Uppsala

Montelius, Anders; Blomquist, Erik; Naeser, Peter; Brahme, Anders; Carlsson, Jörgen; Carlsson, Axel C.; Graffman, S.; Grusell, Erik; Hallén, S.; Jakobsson, P-J; Jung, B.; Larsson, B.; Nilsson, Berith; Rikner, Göran; Russell, Kellie R.; Svensson, Roger

doi:10.3109/02841869109092450

Cited by 34 publications

(17 citation statements)

References 5 publications

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“…Today multileaf collimation combined with scanned beams is available for clinical electron and photon therapy through the Racetrack accelerator (38), but it has also been developed for ion beam therapy (39) proton therapy (40,41) and been proposed for neutron therapy (42). It is clear that such techniques have important advantages with regard to the speed and quality of the treatment and may be increasingly implemented and used for radiation therapy in the new millennium.…”

Section: Comparison Of New Radiation Modalities and Irradiation Technmentioning

confidence: 99%

Development of Radiation Therapy Optimization

Brahme

2000

Acta Oncologica

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Section: Comparison Of New Radiation Modalities and Irradiation Technmentioning

confidence: 99%

Development of Radiation Therapy Optimization

Brahme

2000

Acta Oncologica

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“…The first patient at TSL was treated in April 1989 with a horizontal narrow proton beam of 72 MeV to 54.5 Gy in four fractions using a single field technique for the treatment of ocular melanoma. 159 The facility now has become part of Uppsala Academic Hospital and has also been treating patients to other sites in the brain including arteriovenous malformations ͑AVMs͒ and meningiomas with the 100 MeV beam since 1991 and 1994, respectively.…”

Section: Ivi Proton Radiosurgerymentioning

confidence: 99%

The role of medical physicists in developing stereotactic radiosurgery

et al. 2008

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This article is a tribute to the pioneering medical physicists over the last 50 years who have participated in the research, development, and commercialization of stereotactic radiosurgery (SRS) and stereotactic radiotherapy utilizing a wide range of technology. The authors have described the evolution of SRS through the eyes of physicists from its beginnings with the Gamma Knife in 1951 to proton and charged particle therapy; modification of commercial linacs to accommodate high precision SRS setups; the multitude of accessories that have enabled fine tuning patients for relocalization, immobilization, and repositioning with submillimeter accuracy; and finally the emerging technology of SBRT. A major theme of the article is the expanding role of the medical physicist from that of advisor to the neurosurgeon to the current role as a primary driver of new technology that has already led to an adaptation of cranial SRS to other sites in the body, including, spine, liver, and lung. SRS continues to be at the forefront of the impetus to provide technological precision for radiation therapy and has demonstrated a host of downstream benefits in improving delivery strategies for conventional therapy as well. While this is not intended to be a comprehensive history, and the authors could not delineate every contribution by all of those working in the pursuit of SRS development, including physicians, engineers, radiobiologists, and the rest of the therapy and dosimetry staff in this important and dynamic radiation therapy modality, it is clear that physicists have had a substantial role in the development of SRS and theyincreasingly play a leading role in furthering SRS technology.

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“…Two recently introduced treatment methods of particular interest are intraoperative irradiation, now with electrons, and stereotactic radiotherapy (23). Re search at the proton facility at Uppsala has been re sumed, now as a national project, after many years' rebuilding of the synchrocyclotron and the laborato ries (26). The present status of neutron therapy was described and extensively discussed at a symposium in Linköping in 1993 (11,30).…”

Section: The 1990s Present Trendsmentioning

confidence: 99%