The NanoDefiner e-tool — A decision support framework for recommendation of suitable measurement techniques for the assessment of potential nanomaterials

Brüngel, Raphael; Rückert, Johannes; Wohlleben, Wendel; Babick, Frank; Ghanem, Antoine; Gaillard, Claire; Mech, Agnieszka; Rauscher, Hubert; Weigel, Stefan; Friedrich, Christoph M.

doi:10.1109/nmdc.2017.8350509

Cited by 3 publications

(4 citation statements)

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“…This involved systematic shape characterization to conduct all the screening strategy, questioning so, the added value of the VSSA criterion if finally, accessing to size and particle shape is mandatory for reliable nanomaterial identification. The approach proposed by the Nanodefine project is cautious and it is currently integrated in the Nanodefiner e-tool, 25 a decision support framework for the characterisation of potential nanomaterials. However, it does not seem to allow a wide use of the VSSA criterion in the particular risk assessment context.…”

Section: Introductionmentioning

confidence: 99%

Toward an operational methodology to identify industrial-scaled nanomaterial powders with the volume specific surface area criterion

et al. 2019

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Section: Introductionmentioning

confidence: 99%

Toward an operational methodology to identify industrial-scaled nanomaterial powders with the volume specific surface area criterion

et al. 2019

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“…Results of e-tool assessments obtained from independent industrial case studies confirmed its consistency with the underlying NanoDefine DSFS in all cases [14]. In October 2017, the e-tool was released in version 1.0.0 [12]. Currently, it is available in version 1.0.2 and kept up to date in regard to security aspects, reported bugs, wording, and possible revisions of the EC NM recommendation.…”

Section: Discussionmentioning

confidence: 73%

“…The e-tool ( (access 2019-08-16)) [12] was implemented as an expert system for material categorization and aims to support material registration processes. Therefore, it provides MT recommendations for the assessment of specific materials.…”

Section: Introductionmentioning

confidence: 99%

NanoDefiner e-Tool: An Implemented Decision Support Framework for Nanomaterial Identification

et al. 2019

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The European Commission’s recommendation on the definition of nanomaterial (2011/696/EU) established an applicable standard for material categorization. However, manufacturers face regulatory challenges during registration of their products. Reliable categorization is difficult and requires considerable expertise in existing measurement techniques (MTs). Additionally, organizational complexity is increased as different authorities’ registration processes require distinct reporting. The NanoDefine project tackled these obstacles by providing the NanoDefiner e-tool: A decision support expert system for nanomaterial identification in a regulatory context. It provides MT recommendations for categorization of specific materials using a tiered approach (screening/confirmatory), and was constructed with experts from academia and industry to be extensible, interoperable, and adaptable for forthcoming revisions of the nanomaterial definition. An implemented MT-driven material categorization scheme allows detailed description. Its guided workflow is suitable for a variety of user groups. Direct feedback and explanation enable transparent decisions. Expert knowledge is held in a knowledge base for representation of MT performance criteria and physicochemical particle type properties. Continuous revision ensured data quality and validity. Recommendations were validated by independent case studies on industry-relevant particulate materials. Besides supporting material identification and registration, the free and open-source e-tool may serve as template for other expert systems within the nanoscience domain.

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“…This table is also integrated as a configuration file in the NanoDefiner e-tool, 48 a free software to support the identification of nanomaterials according to the EC NM definition. As the performance of nanoparticle sizing techniques may be improved and new measurement techniques may become available in the future, the table can be updated and complemented according to the latest developments and thus be kept up to date.…”

Section: Matching Materials Properties and Experimental Capabilitiesmentioning

confidence: 99%

A technique-driven materials categorisation scheme to support regulatory identification of nanomaterials

et al. 2019

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The NanoDefiner e-tool — A decision support framework for recommendation of suitable measurement techniques for the assessment of potential nanomaterials

Cited by 3 publications

References 2 publications

Toward an operational methodology to identify industrial-scaled nanomaterial powders with the volume specific surface area criterion

Toward an operational methodology to identify industrial-scaled nanomaterial powders with the volume specific surface area criterion

NanoDefiner e-Tool: An Implemented Decision Support Framework for Nanomaterial Identification

A technique-driven materials categorisation scheme to support regulatory identification of nanomaterials

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