The Myotonia Acquisita in Relation to the Postneuritic Muscular Hypertrophies

Isolated muscle hypertrophy as a sign of radicular or peripheral nerve injury.

“…Such a pathogenesis has also been postulated in muscle hypertrophy of polyneuropathies with "pseudomyotonia". '9 33 3' Similarly, Valenstein et al" noted that a patient with chronic recurrent polyneuropathy showed the most spontaneous activity in those muscles which were hypertrophied. It could be assumed that the considerably hypertrophic muscle fibres in our biopsies were the ones which produced the spontaneous activity.…”

Myotonic Human Musculature: Stimulation with Depolarizing Agents: II. A Clinico‐Pharmacological Study

“…If the presence of multiple end plates is a pre-requisite for myotonia, a n active myotonic phenomenon should be manifest during re-innervation of the musculature. This is indeed the case (12,22). However, no investigations have been made to ascertain whether multiple end plates and myotonia co-exist in the same muscles after re-innervation.…”

Skeletal muscle cramps

“…This condition has an interesting history. It has been described recurrently, in recent times conspicuously by Krabbe,5 and more recently by Worster-Drought and Sargent. 7 Denny-Brown 2 has commented on its mechanism.…”