The Mutual Regulatory Role of Ferroptosis and Immunotherapy in Anti-tumor Therapy
Zhiguo Mao,
Yilong Hu,
Yinan Zhao
et al.
Abstract:Ferroptosis is a form of cell death that is triggered by the presence of ferrous ions and is characterized by lipid peroxidation induced by these ions. The mechanism exhibits distinct morphological characteristics compared to apoptosis, autophagy, and necrosis. A notable aspect of ferroptosis is its ability to inhibit uncontrolled tumor replication and immortalization, especially in malignant, drug-resistant, and metastatic tumors. Additionally, immunotherapy, a novel therapeutic approach for tumors, has been … Show more
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