The MRGPR family of receptors in immunity

Gour, Naina; Dong, Xinzhong

doi:10.1016/j.immuni.2023.12.012

Immunity

2024

DOI: 10.1016/j.immuni.2023.12.012

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The MRGPR family of receptors in immunity

Naina Gour,

Xinzhong Dong

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2024

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Cited by 2 publications

References 125 publications

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Nutritional Implications of Mast Cell Diseases

Harris,

Nasar,

Finnerty

2024

Journal of the Academy of Nutrition and Dietetics

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Nutritional Implications of Mast Cell Diseases

Harris,

Nasar,

Finnerty

2024

Journal of the Academy of Nutrition and Dietetics

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The role of nociceptive neurons in allergic rhinitis

Cong,

Lv,

2024

Front. Immunol.

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Allergic rhinitis (AR) is a chronic, non-infectious condition affecting the nasal mucosa, primarily mediated mainly by IgE. Recent studies reveal that AR is intricately associated not only with type 2 immunity but also with neuroimmunity. Nociceptive neurons, a subset of primary sensory neurons, are pivotal in detecting external nociceptive stimuli and modulating immune responses. This review examines nociceptive neuron receptors and elucidates how neuropeptides released by these neurons impact the immune system. Additionally, we summarize the role of immune cells and inflammatory mediators on nociceptive neurons. A comprehensive understanding of the dynamic interplay between nociceptive neurons and the immune system augments our understanding of the neuroimmune mechanisms underlying AR, thereby opening novel avenues for AR treatment modalities.

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The MRGPR family of receptors in immunity

Cited by 2 publications

References 125 publications

Nutritional Implications of Mast Cell Diseases

Nutritional Implications of Mast Cell Diseases

The role of nociceptive neurons in allergic rhinitis

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