The Moth-Eaten Alopecia of Secondary Syphilis A Histopathological Study of 12 Patients

Jordaan, H.F.; Louw, Mercia

doi:10.1097/00000372-199504000-00008

Cited by 52 publications

(28 citation statements)

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“…One of the proposals has been the presence of eosinophils. Some studies, such as the one by Jordaan and Louw, 69 describe the presence of eosinophils in syphilitic alopecia, whereas other authors, such as Lee and Hsu 70 report their absence and consider this criterion useful for differential diagnosis with alopecia areata.…”

Section: Syphilitic Alopeciamentioning

confidence: 99%

Histologic Features of Alopecias–Part I: Nonscarring Alopecias

Bernárdez

Molina-Ruiz

Requena

2015

Actas Dermo-Sifiliográficas (English Edition)

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The diagnosis of disorders of the hair and scalp can generally be made on clinical grounds, but clinical signs are not always diagnostic and in some cases more invasive techniques, such as a biopsy, may be necessary. This 2-part article is a detailed review of the histologic features of the main types of alopecia based on the traditional classification of these disorders into 2 major groups: scarring and nonscarring alopecias. Scarring alopecias are disorders in which the hair follicle is replaced by fibrous scar tissue, a process that leads to permanent hair loss. In nonscarring alopecias, the follicles are preserved and hair growth can resume when the cause of the problem is eliminated. In the first part of this review, we describe the histologic features of the main forms of nonscarring alopecia. Since a close clinical-pathological correlation is essential for making a correct histologic diagnosis of alopecia, we also include a brief description of the clinical features of the principal forms of this disorder.

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Section: Syphilitic Alopeciamentioning

confidence: 99%

Histologic Features of Alopecias–Part I: Nonscarring Alopecias

Bernárdez

Molina-Ruiz

Requena

2015

Actas Dermo-Sifiliográficas (English Edition)

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“…In the moth-eaten alopecia of secondary syphilis, the histopathology is similar to that of AA [47,48] and therefore the trichoscopy may be mimicking. However, so far there is no report of trichoscopy in syphilitic alopecia.…”

Section: Trichoscopic Clues For Diagnosing Other Hair Loss Diseasesmentioning

confidence: 91%

Trichoscopy: a new frontier for the diagnosis of hair diseases

Inui¹

2012

Expert Review of Dermatology

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“…Alopecia syphilitica is a rare and rather uncommon manifestation of secondary syphilis occurring in only about 5 % of syphilis patients [2]. It can be the only clinical symptom of syphilis infection and mimic alopecia areata in clinical course or on histopathological findings [3]. Syphilitic hair loss, suggested to be caused by the direct infection of hair follicles by Treponema pallidum [4], is non-inflammatory and noncicatricial and typically presents in a diffuse or in a moth-eaten pattern with multiple patches of non-scarring alopecia, or in a combination of both [5,6].…”

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confidence: 99%