The Morbidity of the 34- to 35-Week Gestation: Should We Reexamine the Paradigm?

Gladstone, Igor M.; Katz, Vern L.

doi:10.1055/s-2004-820503

Cited by 10 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, the number of newborns necessary to detect cases of this disease would have to be high. In the present series no cases of severe pulmonary complications such as bronchopulmonary dysplasia or pulmonary hemorrhage were observed, a finding that might be explained by the small sample size since these complications are also rare in this gestational age group [25]. The absence of neonatal death in the present sample is probably due to the low mortality of these newborns, which is approximately 7.7 per 1000 live births [21].…”

Section: Discussionmentioning

confidence: 64%

Neonatal Outcomes of Late‐Preterm Birth Associated or Not with Intrauterine Growth Restriction

Rocha

Bittar

Zugaib

2010

Obstetrics and Gynecology International

View full text Add to dashboard Cite

Objective. To compare neonatal morbidity and mortality between late-preterm intrauterine growth-restricted (IUGR) and appropriate-for-gestational-age (AGA) infants of the comparable gestational ages (GAs). Methods. We retrospectively analyzed neonatal morbidity and mortality of 50 singleton pregnancies involving fetuses with IUGR delivered between 34 and 36 6/7 weeks of GA due to maternal and/or fetal indication. The control group consisted of 36 singleton pregnancies with spontaneous preterm delivery at the same GA, in which the infant was AGA. Categorical data were compared between IUGR and AGA pregnancies by X 2 analysis and Fisher's exact test. Ordinal measures were compared using the Kruskal-Wallis test. Results. The length of stay of newborns in the nursery, as well as the need for and duration of hospitalization in the neonatal intensive care unit, was longer in the group with IUGR. Transient tachypnea of the newborn or apnea rates did not differ significantly between the IUGR and AGA groups. IUGR infants were found to be at a higher risk of intraventricular hemorrhage. No respiratory distress syndrome, pulmonary hemorrhage or bronchopulmonary dysplasia was observed in either group. The frequency of sepsis, thrombocytopenia and hyperbilirubinemia was similar in the two groups. Hypoglycemia was more frequent in the IUGR group. No neonatal death was observed. Conclusion. Our study showed that late-preterm IUGR infants present a significantly higher risk of neonatal complications when compared to late-preterm AGA infants.

show abstract

Section: Discussionmentioning

confidence: 64%

Neonatal Outcomes of Late‐Preterm Birth Associated or Not with Intrauterine Growth Restriction

Rocha

Bittar

Zugaib

2010

Obstetrics and Gynecology International

View full text Add to dashboard Cite

show abstract

“…Preeclampsia, which is characterized by hypertension and proteinuria during the latter half of pregnancy and can only be resolved by delivery1 is a major cause of maternal or perinatal morbidity and mortality.…”

Section: Introductionmentioning

confidence: 99%

The Relationship between Aldosterone to Renin Ratio and RI Value of the Uterine Artery in the Preeclamptic Patient vs. Normal Pregnancy

et al. 2008

View full text Add to dashboard Cite

PurposePlasma levels of renin, angiotensin II and aldosterone are increased during normal pregnancy. However, these values in preeclampsia are decreased to nearly that of a nonpregnant subject, and vascular sensitivity to angiotensin II is increased. In preeclampsia, aldosterone is decreased less than rennin. Therefore current studies were undertaken to determine the relationship between aldosterone to renin ratio (ARR) and uterine artery perfusion via RI value.Materials and MethodsIn this study, the relationship between plasma aldosterone and renin concentration was determined in 27 preeclamptic women and 50 normal pregnant women, whose gestational weeks were matched. The aldosterone to renin ratio was calculated and compared between the two groups. Doppler velocimetry of the uterine artery, which was used to calculate resistance index (RI), was performed on all subjects. The relationship between ARR and RI value was reviewed.ResultsIn the preeclampsia group, RI value of the uterine artery was significantly higher than that of normal pregnant women. Both plasma renin and aldosterone concentrations were lower in the preeclampsia group. However, the ratio of these two parameters was significantly higher (38.3 vs. 16.1, p < 0.001); the greater ARR, the higher the RI of the uterine artery (r2=0.053, p = 0.048).ConclusionThis study demonstrates that a high aldosterone to renin ratio may have a negative effect on perfusion of the uterine artery and play an important role in the pathophysiology of preeclampsia.

show abstract

“…Preeclampsia, intrauterine growth restriction (IUGR), and preterm delivery are major causes of maternal or perinatal morbidity and mortality during the latter half of pregnancy 1,2. The exact pathophysiology underlying these conditions remains unknown.…”

Section: Introductionmentioning

confidence: 99%

Uterine Artery Doppler Velocimetry During Mid-second Trimester to Predict Complications of Pregnancy Based on Unilateral or Bilateral Abnormalities

et al. 2005

View full text Add to dashboard Cite

We performed this study to evaluate uterine artery Doppler velocimetry (UADV) measurement of unilateral or bilateral abnormalities as a predictor of complications in pregnancy during the mid-second trimester (20-24 weeks). We enrolled 1,090 pregnant women who had undergone UADV twice: once between the 20th and 24th week (1st stage) and again between the 28th and 32nd week (2nd stage) of pregnancy, and then delivered at Yonsei Medical Center. UADV was performed bilaterally. Follow-up UADV was performed between the 28th and 32nd week, and the frequencies of pregnancy-induced hypertension (PIH), fetal growth restriction (FGR), and preterm delivery (before 34 weeks of gestation) were determined. Chi-squared and t-tests were used where appropriate, with p < .05 considered significant. According to the results of UADV performed between 20-24 weeks of gestation, 825 women (75.7%) were included in the normal group, 196 (18.0%) in the unilateral abnormality group, and 69 (6.3%) in the bilateral abnormality group. The incidences of FGR were 8.0%, 10.2%, and 26.1%, and the incidences of PIH were 0.1%, 3.6%, and 14.5%, respectively. The incidence of PIH was significantly lower in the normal group. The incidences of preterm delivery were 2.2%, 5.6%, and 8.7%, respectively. PIH developed in 46.7% of patients with bilateral abnormal findings in both the 1st and 2nd stage tests, and developed in none of the patients with normal findings in both tests. Abnormal results found by UADV performed between the 20-24th weeks of pregnancy, such as high S/D ratios regardless of placental location and the presence of an early diastolic notch, were associated with significant increases in the incidences of intrauterine growth restriction (IUGR) and PIH. This was true for both bilateral and unilateral abnormalities. Abnormal findings in bilateral UADV during the second trimester especially warrant close follow up for the detection of subsequent development of pregnancy complications.

show abstract

The Morbidity of the 34- to 35-Week Gestation: Should We Reexamine the Paradigm?

Cited by 10 publications

References 13 publications

Neonatal Outcomes of Late‐Preterm Birth Associated or Not with Intrauterine Growth Restriction

Neonatal Outcomes of Late‐Preterm Birth Associated or Not with Intrauterine Growth Restriction

The Relationship between Aldosterone to Renin Ratio and RI Value of the Uterine Artery in the Preeclamptic Patient vs. Normal Pregnancy

Uterine Artery Doppler Velocimetry During Mid-second Trimester to Predict Complications of Pregnancy Based on Unilateral or Bilateral Abnormalities

Contact Info

Product

Resources

About