The modulator role of Urtica dioica on deleterious effects of retinoic acid high doses on histological parameters and fertilization of rats

Du, Shuli; Wang, Lijuan; Wang, Yinghui; Jin, Y.; Wang, Aijing; Lv, Cuiting; Abedi-Firouzjah, Razzagh

doi:10.1016/j.heliyon.2023.e17277

Heliyon

2023

DOI: 10.1016/j.heliyon.2023.e17277

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The modulator role of Urtica dioica on deleterious effects of retinoic acid high doses on histological parameters and fertilization of rats

Shuli Du

Lijuan Wang

Yinghui Wang³

et al.

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2024

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Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials

Abi Sleiman,

Younes,

Hajj

et al. 2024

IJMS

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While conventional medicine has advanced in recent years, there are still concerns about its potential adverse reactions. The ethnopharmacological knowledge established over many centuries and the existence of a variety of metabolites have made medicinal plants, such as the stinging nettle plant, an invaluable resource for treating a wide range of health conditions, considering its minimal adverse effects on human health. The aim of this review is to highlight the therapeutic benefits and biological activities of the edible Urtica dioica (UD) plant with an emphasis on its selective chemo-preventive properties against various types of cancer, whereby we decipher the mechanism of action of UD on various cancers including prostate, breast, leukemia, and colon in addition to evaluating its antidiabetic, microbial, and inflammatory properties. We further highlight the systemic protective effects of UD on the liver, reproductive, excretory, cardiovascular, nervous, and digestive systems. We present a critical assessment of the results obtained from in vitro and in vivo studies as well as clinical trials to highlight the gaps that require further exploration for future prospective studies.

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Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials

Abi Sleiman,

Younes,

Hajj

et al. 2024

IJMS

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The modulator role of Urtica dioica on deleterious effects of retinoic acid high doses on histological parameters and fertilization of rats

Cited by 1 publication

References 47 publications

Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials

Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials

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