The mid-term clinical outcomes of total knee arthroplasty in the management of end-stage hemophilic arthropathy

Kalkışım, Muhammet; Okutan, Ahmet Emin; Sarac, Unal; Kerimoğlu, Servet

doi:10.5152/j.aott.2022.21131

Cited by 1 publication

(4 citation statements)

References 34 publications

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“…Despite three cases out of 52 (5.77%) showing aseptic loosening in THA, there was no necessity for revision due to the limited follow‐up period. This is comparable to previous investigations reporting such rates to be 4%–10.2% 16–19 . The lower rate of revision is consistent with a relatively low rate of deep infection.…”

Section: Discussionsupporting

confidence: 90%

“…This is comparable to previous investigations reporting such rates to be 4%-10.2%. [16][17][18][19] The lower rate of revision is consistent with a relatively low rate of deep infection. It should be noted that the follow-up period of this study is relatively short, as aseptic loosening of prosthesis leading to revision would increase over time.…”

Section: Adverse Events and Complicationssupporting

confidence: 56%

“…Knee extension was regained in affected knees in all groups, which was thought to be one of the crucial factors that might improve hemophilia patients' knee function and life quality. Similarly, THA in hemophilia patients demonstrated a significant increase in ROM and reduction of pain, as well as a significant improvement of the HSS scores reported by several studies 16–19,24 . In one study, the Knee Society functional score, flexion contracture, and ROM improved significantly during the last follow‐up and the functional results were reported to be worse in patients with severely stiff knee joints 24 .…”

Section: Discussionmentioning

confidence: 83%

“…Similarly, THA in hemophilia patients demonstrated a significant increase in ROM and reduction of pain, as well as a significant improvement of the HSS scores reported by several studies. [16][17][18][19]24 In one study, the Knee Society functional score, flexion contracture, and ROM improved significantly during the last follow-up and the functional results were reported to be worse in patients with severely stiff knee joints. 24 However, most of these reports studied TKA and THA separately.…”

Section: Improvements In Clinical and Movement Outcomesmentioning

confidence: 99%

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A Retrospective, Long‐term Follow‐up of the Clinical Outcomes and Cost‐effectiveness of Single‐anesthetic Multiple Total Joint Procedures in Hemophilic Arthropathy

Peng

Jiang

Zheng

et al. 2023

Orthopaedic Surgery

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Objective: Although total joint replacement (TJR) procedures are efficacious, perioperative high-dose factors replacement therapy (FRT) to avoid catastrophic bleeding represents a significant hurdle, particularly for patients with multiple joint affection. Double simultaneous bilateral TJRs were reported as safe and cost-effective. However, little is known about multiple TJRs. The feasibility and effects remain debatable. Surgeons need to weigh the high cost of FRT against safety. Accordingly, we aimed to evaluate the clinical outcomes and cost-effectiveness of single-anesthetic multiple-joint procedures of lower limbs in end-stage hemophilic arthropathy. Methods:Our retrospective cohort study retrieved data from an inpatient database of patients with hemophilia who underwent total knee arthroplasty (TKA), total hip arthroplasty (THA), and/or ankle arthrodesis from January 2000 to April 2016. Complications, hospital stays, transfusion, doses of clotting factor, medical costs, range of motion (ROM), Harris hip scores (HHSs) and Hospital for special surgery knee scores (HSSs) were recorded. A P value < 0.05 was considered significant.Results: A total number of 81 patients were included in this study, among which 89 TKAs and 52 THAs were performed. Compared to the single TJR group, the simultaneous multiple TJR group showed a significantly higher rate of blood transfusions (P < 0.05). But no significant differences were found in the length of hospital stays, factor consumption, hospitalization costs excluding prosthesis expenses, and total complication rates. Finally, similar postoperative ROM, HHS, and HSS were witnessed in two groups (P value > 0.05). Conclusion:Our data indicated that simultaneous multiple TJRs are a safe and cost-effective choice for treating hemophilic patients with multiple HA-affected lower limb joints.

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Section: Discussionsupporting

confidence: 90%