The microsurgical treatment of cranio-orbital tumors assisted by intraoperative electrophysiologic monitoring and neuronavigation

Gao, Dakuan; Fei, Zhou; Jiang, Xiaofan; Zhang, Xiang; Liu, Weiping; Fu, Ling; Li, Bing; Liang, Jingwen

doi:10.1016/j.clineuro.2012.01.050

Cited by 17 publications

(10 citation statements)

References 23 publications

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“…No permanent ocular loss was found in two studies. [5,17] In our study, partial or complete improvement was achieved in three of four patients who had lost their vision before surgery. As a result of the operations performed, one patient had permanent vision loss.…”

Section: Discussionsupporting

confidence: 47%

“…In a study with 38 patients, in terms of visual field loss, no postoperative deterioration was observed and visual field defects in two patients were not reportedly improved. [17] In our series, the preoperative visual field defects in three of four patients improved significantly. In three patients who did not have visual field impairment before the operation, de novo defects developed.…”

Section: Discussionmentioning

confidence: 46%

“…[5] In another series of 38 cases, permanent diplopia was detected in one patient who had not diplopia preoperatively. [17] Ocular movement disorder was resolved in two of three patients. Three patients had ocular movement disturbances due to the operation.…”

Section: Discussionmentioning

confidence: 87%

“…In another study, exophthalmos was not seen in any patient who had not this disorder preoperatively. [17] Although these smaller numbers are not suitable for statistical analysis, it can be said that there is no significant difference regarding complications.…”

Section: Discussionmentioning

confidence: 99%

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Cranio-Orbital Tumors; Clinical Results and Surgical Approach

Kılıç¹

2018

Sisli Etfal

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O rbit is an anatomical structure measuring approximately 40 mm in height, 45 mm in depth and up to 30 ml in volume and confined with cranial, facial and nasal. Bones Cranio-orbital tumors can be divided schematically into three groups. Primary lesions originate from structures within the orbit. Secondary lesions are intracranial tumors and paranasal sinuses that extend into the orbit from surrounding structures. The third group is metastatic tumors. [1] Orbital tumors can be divided into three categories according to their anotomic location: 1) Intraconal (within the cone of extraocular muscles), 2) extraconal, and 3) intracanalicular (within the optic canal) tumors. This classification of localization is made according to the cone shape starting from the posterior of the eye globe made by extraocular muscles and ending in the Zinn ring. [2] In terms of surgical approach to orbital tumors, three surgical approaches can be applied: 1) Transorbital approaches are generally used for tumors in the anterior part of the orbit. [3] 2) Extraorbital-transcranial approaches are mostly used for lesions located on the posterior part of the orbit, lateral and superior optic nerve. [4, 5] 3) Endonasal transcranial approaches can be used for tumors located in the medial part of the orbita. [6, 7] The extraorbital-transcranial approaches are mainly divided into lateral and anterior Objectives: In this study, we aimed to share the surgical approaches and clinical experiences of cranio-orbital tumors, which are surgically difficult anatomies. Methods: A total of 22 orbital tumors with extraorbital-transcranial pathology between January 2004 and December 2017 were retrospectively reviewed. Information was obtained from hospital, operation and outpatient records for this study. Preoperative demographic data, ophthalmologic examination findings, clinical and radiological findings were recorded. All patients had cranial magnetic resonance and cranial computerised tomography examinations at this time. The location of the tumor, its size and its relation to neighboring structures were recorded in the light of these examinations. Results: The lateral approach was performed in 12 cases. The lateral approach was performed with frontotemporal craniotomy. Because of the lateral inferior location of the tumor in three of 12 cases, zygoma osteotomy was added to classical osteotomy. In 10 cases, the anterior approach was applied and the frontal craniotomy was found sufficient in seven cases. In three cases subfrontal craniotomy was added to classical craniotomy. Conclusion: The findings obtained in this study suggest that high resection rates can be achieved with appropriate surgical intervention in orbital tumors requiring a transcranial surgical approach. The most important factor in surgical planning is the location of the tumor. The size of the tumor and the expectation of the percentage of surgical removal are the other important factors. In our series, it has reached high excision ratio in most cases with low complication rate, good visu...

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Section: Discussionsupporting

confidence: 47%

Section: Discussionmentioning

confidence: 46%

Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

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Cranio-Orbital Tumors; Clinical Results and Surgical Approach

Kılıç¹

2018

Sisli Etfal

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“…Chao et al proposed that tricetin inhibits GBM cell migration and invasion by reducing MMP‐2 expression . Regarding other flavonoid derivatives, Lin et al and Gao et al have demonstrated that resveratrol reduced TPA‐induced MMP‐9 expression in SCC‐9 cells and cerebral ischemia reperfusion in mice, respectively . Moreover, our previous reports shown that Rubus idaeus extract and Leucaena leucocephala extract exerted an inhibitory effect of migration and invasion in oral cancer cells .…”

Section: Discussionmentioning

confidence: 94%

Tricetin suppresses human oral cancer cell migration by reducing matrix metalloproteinase‐9 expression through the mitogen‐activated protein kinase signaling pathway

Chung

Chuang

Teng

et al. 2017

Environmental Toxicology

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Tricetin is a flavonoid derivative and a potent anti-inflammatory and anticancer agent. However, the molecular mechanism underlying the effects of tricetin on human oral cancer cell migration remains unclear. The cell migration and invasion abilities of three oral cancer cell lines (SCC-9, HSC-3, and OECM-1) were analyzed using Boyden chamber migration assays. Our results demonstrated that tricetin attenuates 12-O-tetradecanoylphorbol-13-acetate-induced SCC-9, HSC-3, and OECM-1 cell invasiveness and migration by reducing matrix metalloproteinase (MMP)-9 enzyme activity. The reverse transcription polymerase chain reaction and luciferase reporter assay revealed that tricetin downregulates the mRNA expression and promoter activity of MMP-9. In addition, Western blot analysis revealed that tricetin significantly reduced the levels of phosphorylated c-Jun N-terminal kinase (JNK) 1/2 and p38 levels but not those of extracellular signal-regulated kinase 1/2. In conclusion, this study demonstrated that tricetin suppresses MMP-9 enzymatic activity by downregulating the p38/JNK1/2 pathway and might be a beneficial chemopreventive agent.

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Computer Assisted Surgery and Navigation in Cranio-orbital Resection and Reconstruction

Acero

Leyva

2021

Innovations and New Developments in Craniomaxillofacial Reconstruction

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The microsurgical treatment of cranio-orbital tumors assisted by intraoperative electrophysiologic monitoring and neuronavigation

Cited by 17 publications

References 23 publications

Cranio-Orbital Tumors; Clinical Results and Surgical Approach

Cranio-Orbital Tumors; Clinical Results and Surgical Approach

Tricetin suppresses human oral cancer cell migration by reducing matrix metalloproteinase‐9 expression through the mitogen‐activated protein kinase signaling pathway

Computer Assisted Surgery and Navigation in Cranio-orbital Resection and Reconstruction

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