The microbial network property as a bio-indicator of antibiotic transmission in the environment

Gao, Qun; Gao, Shuhong; Bates, Colin T.; Zeng, Yufei; Lei, Jiesi; Su, Hang; Dong, Qiang; Qin, Ziyan; Zhao, Jianshu; Zhang, Qiuting; Ning, Daliang; Huang, Yi; Zhou, Jizhong; Yang, Yunfeng

doi:10.1016/j.scitotenv.2020.143712

Cited by 33 publications

(15 citation statements)

References 77 publications

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“…For example, efficient and complete removal of PBDEs is implicated to be associated with the successful establishment of robust linkages between the augmented Dehalococcoides and other indigenous microorganisms. By contrast, the accumulation of toxic intermediates (di-BDEs in TZ50-augmented sediments) may lead to changes in microbial networks, as a potential stress-defense mechanism . The community assembly analysis further indicates that bioaugmentation could result in a higher contribution of deterministic processes to community assembly; however, it is still much lower than that of stochastic processes in this study.…”

Section: Discussionmentioning

confidence: 53%

Efficient and Complete Detoxification of Polybrominated Diphenyl Ethers in Sediments Achieved by Bioaugmentation with Dehalococcoides and Microbial Ecological Insights

Chen

et al. 2022

Environ. Sci. Technol.

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Polybrominated diphenyl ethers (PBDEs) are prevalent environmental pollutants, but bioremediation of PBDEs remains to be reported. Here we report accelerated remediation of a penta-BDE mixture in sediments by bioaugmentation with Dehalococcoides mccartyi strains CG1 and TZ50. Bioaugmentation with different amounts of each Dehalococcoides strain enhanced debromination of penta-BDEs compared with the controls. The sediment microcosm spiked with 6.8 × 106 cells/mL strain CG1 showed the highest penta-BDEs removal (89.9 ± 7.3%) to diphenyl ether within 60 days. Interestingly, co-contaminant tetrachloroethene (PCE) improved bioaugmentation performance, resulting in faster and more extensive penta-BDEs debromination using less bioinoculants, which was also completely dechlorinated to ethene by introducing D. mccartyi strain 11a. The better bioaugmentation performance in sediments with PCE could be attributed to the boosted growth of the augmented Dehalococcoides and capability of the PCE-induced reductive dehalogenases to debrominate penta-BDEs. Finally, ecological analyses showed that bioaugmentation resulted in more deterministic microbial communities, where the augmented Dehalococcoides established linkages with indigenous microorganisms but without causing obvious alterations of the overall community diversity and structure. Collectively, this study demonstrates that bioaugmentation with Dehalococcoides is a feasible strategy to completely remove PBDEs in sediments.

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Section: Discussionmentioning

confidence: 53%

Efficient and Complete Detoxification of Polybrominated Diphenyl Ethers in Sediments Achieved by Bioaugmentation with Dehalococcoides and Microbial Ecological Insights

Chen

et al. 2022

Environ. Sci. Technol.

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“…This could indicate that manure promotes horizontal transfer of ARGs, which is further supported by an analysis of cooccurrence and co-exclusion of bacteria throughout the samples that showed a higher level of connection between bacteria in manure-amended soils. The clustering coefficient, transitivity and density of the bacterial network increased with higher antibiotic concentrations [77]. These phenomena were reported to last over time.…”

Section: From Pig To Environmentmentioning

confidence: 81%

Antibiotic Resistance: From Pig to Meat

et al. 2021

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Pork meat is in high demand worldwide and this is expected to increase. Pork is often raised in intensive conditions, which is conducive to the spread of infectious diseases. Vaccines, antibiotics, and other biosafety measures help mitigate the impact of infectious diseases. However, bacterial strains resistant to antibiotics are more and more frequently found in pig farms, animals, and the environment. It is now recognized that a holistic perspective is needed to sustainably fight antibiotic resistance, and that an integrated One Health approach is essential. With this in mind, this review tackles antibiotic resistance throughout the pork raising process, including their microbiome; many factors of their environment (agricultural workers, farms, rivers, etc.); and an overview of the impact of antibiotic resistance on pork meat, which is the end product available to consumers. Antibiotic resistance, while a natural process, is a public health concern. If we react, and act, collectively, it is expected to be, at least partially, reversible with judicious antibiotic usage and the development of innovative strategies and tools to foster animal health.

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“…In this study, the networks of rhizosphere bacterial communities in both varieties had a nonrandom pattern with increasing CIP concentrations (Figure C), reflecting that the deterministic process imposed by CIP stress played more important roles in microbial interactions. CIP exposure decreased the network complexity of the rhizosphere bacterial community in the two varieties (Table S3), which might be attributed to the reduced bacterial coexistence and functional redundancy of bacterial taxa by antibiotic stress, suggesting that the bacterial community development was driven by biotic interactions . Generally, higher antibiotic stress can lead to reduced diversity of bacterial communities, simplifying the community structure and decreasing species connectivity .…”

Section: Discussionmentioning

confidence: 97%

“…Nevertheless, we found that the percentage of positive correlations dominated and increased with increasing CIP stress in the bacterial interactions in the rhizospheres of the two varieties, especially in the HAV rhizosphere (Table S3), suggesting that the interaction among the rhizosphere bacteria caused by CIP stress was mainly cooperative. The cooperation between bacterial taxa may contribute to the resilience of bacterial communities in response to antibiotic stress . Hence, the larger percentage of positive correlations in the HAV rhizosphere than in the LAV rhizosphere under the high-CIP concentration (C3) might relate to stronger microbial degradation of CIP .…”

Section: Discussionmentioning

confidence: 99%

Mechanism and Association between Microbial Nitrogen Transformation in Rhizosphere and Accumulation of Ciprofloxacin in Choysum (Brassica parachinensis)

Yan,

Xiang,

Zhang

et al. 2023

Environ. Sci. Technol.

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Rhizosphere microbiota are an important factor impacting plant uptake of pollutants. However, little is known about how microbial nitrogen (N) transformation in the rhizosphere affects the uptake and accumulation of antibiotics in plants. Here, we determined recruitment of N transformation functional bacteria upon ciprofloxacin (CIP) exposure, by comparing differences in assembly processes of both rhizospheric bacterial communities and N transformation between two choysum (Brassica parachinensis) varieties differing in CIP accumulation. The low accumulation variety (LAV) of CIP recruited more host bacteria (e.g., Nitrospiria and Nitrolancea) carrying nitrification genes (mainly nxrA) but fewer host bacteria carrying denitrification genes, especially narG, relative to the high accumulation variety (HAV) of CIP. The nxrA and narG abundance in the LAV rhizosphere were, respectively, 1.6−7.8 fold higher and 1.4−3.4 fold lower than those in the HAV rhizosphere. Considering that nitrate can decrease CIP uptake into choysum through competing for the proton motive force and energy, such specific bacteria recruitment in LAV favored the production and utilization of nitrate in its rhizosphere, thus limiting its CIP accumulation with 1.6−2.4 fold lower than the HAV. The findings give insight into the mechanism underlying low pollutant accumulation, filling the knowledge gap regarding the profound effects of rhizosphere microflora and N transformation processes on antibiotic accumulation in crops.

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The microbial network property as a bio-indicator of antibiotic transmission in the environment

Cited by 33 publications

References 77 publications

Efficient and Complete Detoxification of Polybrominated Diphenyl Ethers in Sediments Achieved by Bioaugmentation with Dehalococcoides and Microbial Ecological Insights

Efficient and Complete Detoxification of Polybrominated Diphenyl Ethers in Sediments Achieved by Bioaugmentation with Dehalococcoides and Microbial Ecological Insights

Antibiotic Resistance: From Pig to Meat

Mechanism and Association between Microbial Nitrogen Transformation in Rhizosphere and Accumulation of Ciprofloxacin in Choysum (Brassica parachinensis)

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