The MFMU Cesarean Registry: Factors affecting the success of trial of labor after previous cesarean delivery

Landon, Mark B.; Leindecker, Sharon; Spong, Catherine Y.; Hauth, John C.; Bloom, Steven L.; Varner, Michael W.; Moawad, Atef H.; Caritis, Steve N.; Harper, Margaret; Wapner, Ronald J.; Sorokin, Yoram; Miodovnik, Menachem; Carpenter, Mick; Peaceman, Alan M.; OʼSullivan, Mary J.; Sibai, Bahaeddine M; Langer, Oded; Thorp, John M.; Ramin, Susan M.; Mercer, Brian M.; Gabbe, Steven G.

doi:10.1016/j.ajog.2005.05.066

Cited by 410 publications

(263 citation statements)

References 11 publications

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“…Landon et al did a study including 14529 women to determine the factors which are responsible for successful trial of labor (TOL) in women with previous CS, reported that gestational age < 41 weeks (OR, 1.6; 95% CI, 1.5, 1.8) was a favorable intrapartum factor for successful VBAC. 10 Present study is in concordance with them, demonstrating that only 5% of the patients in VBAC group had gestational age > 40 weeks whereas 20% of the patients in ERCS group had gestational age >40 weeks. Quninones et al in large study of 20,156 patients reported 82% success rate for VBAC for preterm group whereas in our study preterm deliveries were similar in both the groups (p>0.05).…”

Section: Discussionsupporting

confidence: 78%

Study of Factors Associated with Success of Vaginal Birth after Previous One Caesarean Section

Bindal¹

2018

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Section: Discussionsupporting

confidence: 78%

Study of Factors Associated with Success of Vaginal Birth after Previous One Caesarean Section

Bindal¹

2018

jmscr

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“…Table 2 When the timing and duration of oxytocin dose is considered, increasing ranges of maximum oxytocin dose are associated with a progressively increasing risk of uterine rupture in patients attempting VBAC. This association with uterine rupture risk, estimated by time-to-event analysis, is greater in magnitude than that previously described by multivariable models that did not consider time or duration of therapy 2,4,[6][7][8][9] .…”

Section: Resultsmentioning

confidence: 69%

Higher maximum doses of oxytocin are associated with an unacceptably high risk for uterine rupture in patients attempting vaginal birth after cesarean delivery

Cahill

Waterman

Stamilio

et al. 2008

American Journal of Obstetrics and Gynecology

146

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"Higher maximum doses of oxytocin are associated with an unacceptably high risk for uterine rupture in patients attempting vaginal birth after cesarean delivery". American Journal of Obstetrics and Gynecology, 199, 1, 32.e1-32.e5. 2008 Objective: To more precisely estimate the effect of maximum oxytocin dose on uterine rupture risk in patients attempting VBAC by considering timing and duration of therapy.Study design: A nested case-control study was conducted within a multicenter, retrospective cohort study of over 25,000 women with at least one prior cesarean delivery, comparing cases of uterine rupture to controls (no rupture) while attempting VBAC. Time-to-event analyses were performed to examine the effect of maximum oxytocin dose on the risk of uterine rupture considering therapy duration, while adjusting for confounders.Results: Within the nested case-control study of 804 patients, 272 were exposed to oxytocin: 62 cases of uterine rupture and 210 controls. Maximum oxytocin ranges above 20mu/min increased the risk of uterine rupture 4-fold or greater (21-30mu/min: HR=3.92, 95%CI 1.06-14.52; 31-40mu/min: HR=4.57, 95%CI 1.00-20.82).Conclusion: These findings support a maximum oxytocin dose of 20mu/min in VBAC trials to avoid an unacceptably high risk of uterine rupture.

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“…[12][13][14][15] The most dreaded complication of giving a TOLAC (Trial of labour after Cesarean section) is uterine rupture. A systematic review by Hofmeyr et al reported a 1% worldwide prevalence of uterine rupture among women with a previous CS birth.…”

Section: Discussionmentioning

confidence: 99%

Maternal and fetal outcome in pregnant women with previous one lower segment cesarean section

Singh

Dhama

Chaudhary

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONCesarean section is one of the most commonly performed abdominal operations on women in most countries. Cesareans section aims at reducing maternal and fetal mortality and morbidity by virtue of its cautions and careful approach. In many countries, C-sections have become the mode of delivery in over a quarter of all the birth. The World Health Statistics (WHS), 2012, released on Wednesday, said 9% of all births in India were by Caesarian section. The latest figure has gone up by 5% since nearly one in 10 women in India, who gave birth between 2005 and 2010, had gone under the surgical knife.1 Using the data of national family health survey India (1992-93) Mishra and Ramanathan found that among 18 large states two states has CS rate near 15 percent and the rest had less than 5 percent. ABSTRACTBackground: Cesarean section is one of the most commonly performed abdominal operations on women. Because of increasing incidence of Cesarean sections the no. of patients with previous 1 LSCS is also increasing. Thus proper antenatal counseling and institutional delivery should be done. Methods: A prospective observational study was conducted at department of Obstetrics and Gynaecology, LLRM Medical College Meerut during one year period from Nov 2015-May 2016. Participants to study the maternal and fetal outcome in pregnant women with previous one LSCS. 200 pregnant women were included in the study and outcomes were studied. Results: Maternal Outcome: Out of 200 cases 122 patients underwent vaginal birth after Cesarean (VBAC) accounting for 61% and 78 patients underwent 2nd LSCS (76 emergency LSCS and 2 elective LSCS). Out of 76, 55 patients were given trial of VBAC but failed and end up in C-Section showing success rate of 68.92% for VBAC (122 out of 177). Adhesions were found in 21patients out of 78 (26.92%) who underwent LSCS. Uterine rupture seen in 2 patients out of 200 cases (1.0%). Scar dehiscence was seen in 6 out of 78 patients (7.69%). Post-partum Hemorrhage was seen in only 20 (10%) patients. Pre-term Pregnancy occurred in 16 (8%) patients. Caesarean Hysterectomy had to be done in 3 (1.5%) patients. Placenta Previa was seen in 6 out of the 200 patients (3%) and placenta accrete was seen in 1 patient (0.5%). Out of 200 patients, 2 twins were born. The total number of babies born was 201. 8 IUDs occurred out of 201 babies (3.98%) and a total of 25 out of 193 live babies (12.95%) required admission to Neonatal Intensive Care Unit out of which 2 babies died. Conclusions: Cesarean section should not be always followed by a repeat cesarean section. Patient should have hospital delivery in a well-equipped hospital and complications should be diagnosed at an early stage so that maternal and perinatal morbidity and mortality could be prevented.

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The MFMU Cesarean Registry: Factors affecting the success of trial of labor after previous cesarean delivery

Cited by 410 publications

References 11 publications

Study of Factors Associated with Success of Vaginal Birth after Previous One Caesarean Section

Study of Factors Associated with Success of Vaginal Birth after Previous One Caesarean Section

Higher maximum doses of oxytocin are associated with an unacceptably high risk for uterine rupture in patients attempting vaginal birth after cesarean delivery

Maternal and fetal outcome in pregnant women with previous one lower segment cesarean section

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