The Methanol Poisoning Outbreaks in Iran 2018

Aghababaeian, Hamidreza; Ahvazi, Ladan Araghi; Ostadtaghizadeh, Abbas

doi:10.1093/alcalc/agz005

Cited by 53 publications

(65 citation statements)

References 13 publications

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“…The ZO showed signi cant function improvement and pain relief, and no patient were found with infection or nonunion. In another study found that the ZO showed signi cant pain relief compared to other surgical procedures [16] . And in study of Maynou [17] , the ZO was also reported has an excellent results.…”

Section: Discussionmentioning

confidence: 95%

Zadek osteotomy for the treatment of Haglund’s Syndrome

Zheng

Liang

et al. 2020

Preprint

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Background Although several treatment options described in paper, Haglund’s Syndrome (HS) is a challenging common lower extremity disorder. This study reported the clinical outcomes of Zadek osteotomy (ZO) for the treatment of HS. Methods This retrospective study included 19 patients who underwent ZO from January 2016 to June 2018. Patients were evaluated using the American Orthopedic Foot Ankle Society ankle-hindfoot scale (AOFAS), Visual Analogue Scale (VAS), ankle range of motion (AROM), and Chauveaux-Liet (CL) angle preoperatively and at final follow-up visit (16.3 ± 4.2) months. Postoperative complications of patients were also recorded. Results The ZO exhibited a significant improvement (P༜0.05) in preoperative to postoperative AOFAS (from 53.2 ± 5.4 to 86.4 ± 6.5), VAS ( from 6.3 ± 2.1 to 0.9 ± 1.2 ) scores and CL angle (from 18.2 ± 1.3 to 9.4 ± 2.1 ) degrees, the dorsiflexion of AROM (DAROM) (from 23.4 ± 2.3 to 29.4 ± 1.2) degrees. The planter flexion of AROM (PAROM) (from 32.5 ± 3.5 to 33.2 ± 3.4) degrees (P༞0.05). One postoperative complication was observed: a case of hardware pain in healthy patient. The overall rate of satisfaction after surgery was (94.7%). Conclusions ZO is effective and safe procedure for the treatment of HS. This method can be a good option for those patients of HS.

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Section: Discussionmentioning

confidence: 95%

Zadek osteotomy for the treatment of Haglund’s Syndrome

Zheng

Liang

et al. 2020

Preprint

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“…This can be explained by the participants' cultural background and relevant social stigma of alcohol usage for women in Iran. Compared to previous outbreaks [18,19], the age distribution of the population was broader as the study included teenagers as well as senior patients who were in their 70's in some cases. The involvement of the youths may be a matter of concern for social activists in Iran.…”

Section: Discussionmentioning

confidence: 99%

Electrocardiographic findings of methanol toxicity: A cross-sectional study on 356 cases in Iran

Nikoo

Arjangzadeh

Pakfetrat

et al. 2020

Preprint

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Background : Methanol is widely used in industry; however, methanol poisoning is not common. In this regard, a number of outbreaks have been recently reported due to inappropriate processing of alcoholic beverages. Shiraz, a city located in the southern part of Iran, faced one of such outbreaks in 2020 during COVID-19 pandemic. There is no sufficient literature on the electrocardiographic findings in methanol toxicity. This study aimed to address this gap in the literature. Method : A total of 356 cases with methanol toxicity referred to Shiraz University of Medical Science Tertiary Hospitals (Faghihi and Namazi) in March and April, 2020. The clinical findings of blindness and impaired level of consciousness, lab data such as arterial blood gas, electrolytes, and creatinine, and the most common findings from ECGs were collected. Results : The most common ECG findings were J point elevation (68.8%), presence of U wave (59.2%), QTc prolongation (53.2% in males and 28.6% in females), and fragmented QRS (33.7%). An outstanding finding in this study was the presence of myocardial infarction in 5.3% of the cases. This finding, to the best of our knowledge, has only been reported in a few case reports. Brugada pattern (8.1%) and Osborn wave (3.7%) were the other interesting findings. In multivariate analysis, when confounding factors were adjusted, myocardial infarction, atrioventricular conduction disturbances, sinus tachycardia, and the prolonged QTC>500 msecond were four independent factors correlated with methanol toxicity severity measured with arterial blood PH on arterial blood gas measurements, with odds ratios of 12.82, 4.46, 2.32 and 3.15 (P<0.05 for all) , respectively. Conclusion : Electrocardiographic variations during methanol intoxication are remarkable and well-correlated with poisoning severity. Myocardial infarction was an egregious and yet a common concerning finding in this sample, which need to be ruled out in methanol toxicity.

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“…Industrial alcohols available nationwide are labelled as ethanol, methanol or nothing (merely industrial alcohol containing methanol and other toxic alcohols). These issues have been highlighted by Aghababaeian et al (2019) and Ghadirzadeh et al (2019).…”

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confidence: 99%