The Metamorphosis of Acute Renal Failure to Acute Kidney Injury

Pickering, John W.; Endre, Z. H.

doi:10.5772/26705

Cited by 6 publications

(1 citation statement)

References 117 publications

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“…AKI patients have nine-time risk of CKD development and two-time risk of premature death than patients without AKI [2]. In developing countries, like Ghana, AKI affects young individuals who are previously well and thus predisposing them to high morbidity, mortality and high cost [7, 8]. AKI is reversible and treatment inexpensive if detected early and the underlying cause managed aggressively [9].…”

Section: Introductionmentioning

confidence: 99%

Factors associated with acute kidney injury recovery in a tertiary hospital in Ghana: a prospective study

Okyere¹,

Okyere²,

Ndanu³

et al. 2019

Pan Afr Med J

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IntroductionAcute kidney injury (AKI) is a challenging problem in developing countries due to late presentation of its victims to health care facilities. Data on the pattern of AKI, its outcome and factors associated with its recovery is scanty in developing countries therefore impeding AKI management. Aim: to study AKI recovery rate and its associated factors.MethodsAn observational study conducted from September 2013 to June 2014 at Korle-Bu Teaching Hospital (KBTH). Participants were adults, admitted with AKI at KBTH. Kidney Disease: Improving Global Outcomes (KDIGO) criteria was used to diagnose and stage AKI.ResultsMean age (SD) of the participants was 41.9 (± 19.2) years. About a third of the patients (34.6%) were less than 29 years with 30-39 years and 40-60 years constituting 23.0% and 23.6% respectively. Females were in the majority (56.0%). AKI stages I, II and III accounted for 11.0%, 6.8% and 70.7% respectively. Majority, 82.2% of the patients recovered their kidney function. Stage III AKI was significantly associated with decreasing odds of recovery [OR = 0.4, 95%CI = 0.4-2.6, p = 0.002]. In addition, normal blood sodium was associated with recovery from AKI [OR, 95%CI = 2.3, (1.1-5.3), p = 0.043]. Almost half (45.5%) presented with fever whereas 32.5% and 22.5% presented with peripheral oedema and pulmonary oedema respectively.ConclusionThe study demonstrated high kidney function recovery following AKI. Dominant clinical features were fever, peripheral and pulmonary oedema. Advanced stage was associated with poor recovery whereas normal serum sodium level improves kidney function recovery.

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