The metal centre in salen-acridine dyad N₂O₂ ligand–metal complexes modulates DNA binding and photocleavage efficiency

Abstract

Metal centre in a coordination complex modulates DNA binding.

Effect of regio-specific arylamine substitution on novel π-extended zinc salophen complexes: density functional and time-dependent density functional study on DSSC applications

“…The later results meet the reported observations from crystal structural determination, where ZSC adopts distorted square pyramidal geometry with one coordinating solvent molecule bonded to zinc ion, such as DMSO, 52 water, 53 and pyridine. 54 We noted that inclusion of diffusion functions, e.g., 6-311+G(d,p), for optimizing the solvent-free molecules lead to distorted square planar geometry, which differs from distorted square pyramid reported in the literature using 6-311++G(d,p) (with unclear calculation detail). 53 Consequently, the basis sets without diffusion function and pseudopotentials were used throughout this study.…”

Investigation of DNA binding and bioactivities of furan cored Schiff base Cu (II), Ni (II), and Co (III) complexes: Synthesis, characterization and spectroscopic properties

“…The interaction of metal complexes with DNA is associated with an interesting biochemical property of the resulting supramolecular system. [ 15 ] Intercalation encompasses the π–π interaction of aromatic planar part of the molecule with stacked aromatic planes of the nucleic bases. The interaction between the DNA and small metal complexes can be measured by indirect methods such as electronic absorption and fluorescence spectroscopy.…”

Evaluating the substitution effects of bis(β-iminoenolate)copper(ii) complexes on their photophysical, DNA binding/photocleavage, and cytotoxic activities

“…After that, the docking procedure is run on the ligand by keeping all the remaining parameters as default, as mentioned in our earlier paper. 42…”