The Metabolism of Epinephrine Containing Isotopic Carbon. Ii

Schayer, Richard W.; Smiley, Rosa L.; Kaplan, E.H.

doi:10.1016/s0021-9258(18)55509-5

Cited by 59 publications

(2 citation statements)

References 7 publications

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“…Methylamine has been detected in human urine, blood, and tissues. − It can be derived from several metabolic reactions, such as the deamination of adrenaline, sarcosine, creatinine, choline, and lecithin. − It has been suggested that methylamine and other related short-chain aliphatic amines may play a significant role in the central nervous system disturbances observed during hepatic and renal disease, especially when the blood–brain barrier is compromised . In addition, amino functional groups (NH 2 ) occur frequently in biomolecules, for example, amino acids molecules. , The biological functions of methylamine and other biomolecules containing NH 2 are intimately connected to their hydrated structures. − Therefore, studying the hydration of methylamine is essential for biological science.…”

Section: Introductionmentioning

confidence: 99%

Stability of Hydrated Methylamine: Structural Characteristics and H₂N···H–O Hydrogen Bonds

Liu

Huang

et al. 2015

J. Phys. Chem. A

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Methylamine is the simplest aliphatic amine found in human urine, blood, and tissues. It is thought to play a significant part in central nervous system disturbances observed during renal and hepatic disease. In this work we have investigated the methylamine hydration clusters using a basin hopping (BH) algorithm with the density functional theory (DFT). The results presented herein yield a detailed understanding of the structure and stability for a system consisting of one methylamine molecule and up to seven waters: the most stable geometries arise from a fusion of tetramer or pentamer rings; by the geometrical parameters and topological parameters analysis, the strengths of the H2N···H-O hydrogen bonds of the global minima increase as the sizes of clusters increase, except for n = 5 where there is a slight fluctuation. This work may shed light on the form mechanism of methylamine existing in organisms and the hydration structures of larger molecules containing amino functional groups and their interaction with the water molecules nearby.

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Section: Introductionmentioning

confidence: 99%

Stability of Hydrated Methylamine: Structural Characteristics and H₂N···H–O Hydrogen Bonds

Liu

Huang

et al. 2015

J. Phys. Chem. A

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“…Methylamine is mainly produced in other metabolic pathways, which includes the breakedown of adrenaline, sarcosine and creatine (Schayer et al 1952;Davis and De Ropp 1961;Yu and Deng 2000). It can also be ingested by food and beverages as well as by nicotine intake (Yu et al 1998).…”

Section: Catalytic Properties Of Semicarbazide-sensitive Amine Oxidasementioning

confidence: 99%

Semicarbazide Sensitive Amine Oxidase (SSAO)

2002

Wiley Encyclopedia of Molecular Medicine

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Transgenic mice overexpressing Semicarbazide-sensitive amine oxidase (SSAO) have an elevated pulse pressure. Manuscript. Ammonia Diabetes Mellitus SSAO activity in plasma of diabetic patients Capillary occlusion Advanced glycation end products (AGE) AIMS OF THE PRESENT INVESTIGATION Paper I Semicarbazide-sensitive amine oxidase (SSAO) gene expression in alloxan-induced diabetes in mice. Paper II Overexpression of semicarbazide-sensitive amine oxidase (SSAO) in smooth muscle cells leads to an abnormal structure of aortic elastic layers. Paper III Semicarbazide-sensitive amine oxidase (SSAO) in transgenic mice with diabetes. Paper IV Transgenic mice overexpressing Semicarbazide-sensitive amine oxidase (SSAO) have an elevated pulse pressure.

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Methylamin [MAK Value Documentation in German language, 1984]

2012

The MAK‐Collection for Occupational Health and Safety

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Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 10. Lieferung, Ausgabe 1984 Der Artikel enthält folgende Kapitel: Allgemeiner Wirkungscharakter Erfahrungen beim Menschen Tierexperimentelle Befunde Akute Toxizität Subchronische und chronische Toxizität Mutagenität und Carcinogenität Begründung des MAK‐Wertes

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The Metabolism of Epinephrine Containing Isotopic Carbon. Ii

Cited by 59 publications

References 7 publications

Stability of Hydrated Methylamine: Structural Characteristics and H₂N···H–O Hydrogen Bonds

Stability of Hydrated Methylamine: Structural Characteristics and H₂N···H–O Hydrogen Bonds

Semicarbazide Sensitive Amine Oxidase (SSAO)

Methylamin [MAK Value Documentation in German language, 1984]

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The Metabolism of Epinephrine Containing Isotopic Carbon. Ii

Cited by 59 publications

References 7 publications

Stability of Hydrated Methylamine: Structural Characteristics and H2N···H–O Hydrogen Bonds

Stability of Hydrated Methylamine: Structural Characteristics and H2N···H–O Hydrogen Bonds

Semicarbazide Sensitive Amine Oxidase (SSAO)

Methylamin [MAK Value Documentation in German language, 1984]

Contact Info

Product

Resources

About

Stability of Hydrated Methylamine: Structural Characteristics and H₂N···H–O Hydrogen Bonds

Stability of Hydrated Methylamine: Structural Characteristics and H₂N···H–O Hydrogen Bonds