The Metabolism of Ascorbic Acid-1-C14 and Oxalic Acid-C14 in the Rat

Curtin, Constance O'h.; King, C. G.

doi:10.1016/s0021-9258(19)81411-4

Cited by 80 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…DGA was either prepared in solution from commercial dehydroascorbic acid (Homann and Gaffron, 1964) or crystallized as the calcium salt according to Penney and Zilva (1945) and Curtin and King (1955).…”

Section: Methodsmentioning

confidence: 99%

Manganese-catalyzed Oxidations of 2,3-Diketogulonate^*

Homann¹

1965

Biochemistry

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

Manganese-catalyzed Oxidations of 2,3-Diketogulonate^*

Homann¹

1965

Biochemistry

View full text Add to dashboard Cite

“…Reagents. The barium salt of DGA was prepared according to the method of Curtin and King (15), with the following alterations. Ascorbic acid was dissolved in a minimum of distilled water prior to the dropwise addition, with rapid stirring, of an aqueous solution of the proper amount of KI03; Bal2 was used instead of Cal2.…”

mentioning

confidence: 99%

Fluorometric determination of manganese(II) via catalyzed enzymic oxidation of 2,3-diketogulonate

Biddle¹,

Wehry²

1978

Anal. Chem.

View full text Add to dashboard Cite

of 488.1 nm and 514.5 nm are available. Moreover, as the existences of small amounts of foreign metals might cause large errors, a complete separation will become an important requirement.The laser-induced photoacoustic absorption method is applicable to a wide range of liquid samples and application of lasers operating in the UV, visible, and IR is recommended.Further development in surface pre-treatment of piezoelectric ceramic is needed in order to measure materials in concentrated acidic and basic media. Then, ultra trace determinations of various kinds of metals beside cadmium and organic compounds would become possible utilizing the laser-induced photoacoustic absorption method. ACKNOWLEDGMENTWe are greatly indebted to S. Toda and Y. Dokiya of the Faculty of Agriculture, The University of Tokyo, for providing heavy metal-tolerant fungus as samples, and are also grateful to M. Suzuki for her help in atomic absorption measurements. LITERATURE CITEDA fluorometric technique for the determination of Mn(I1) is reported. The specific requirement for Mn(I1) in the peroxidase-catalyzed Oxidation of 2,3-diketogulonate is utilized to produce H,Oz, and the signal observed in the concurrent fluorometric Hz02 "fixed time" assay procedure is related to the Mn( 11) concentration using a modified standard addition method. The utility of this procedure is demonstrated at pH 8.0 and 25 O C in a synthetic seawater matrix wherein the detection limit Is 8 pM Mn( 11); accurate determinations can be performed up to ca. 50 pM Mn(11). Analysis time is less than 30 min.

show abstract

Aliphatic Carboxylic Acids: Saturated

2023

View full text Add to dashboard Cite

Aliphatic carboxylic acids (ACA) include many chemicals with a wide range of biological and industrial functions. Many are nutritionally important, occur naturally, and take part in normal biochemical processes. ACA are commercially important with annual production of over 3, 1, and 1 billion lbs/year for acetic, formic, and acrylic acids alone, respectively. Generally, ACA are of no serious concern, except at very high levels of experimental or accidental exposures, many are designated as GRAS. Primary adverse effects are irritation to skin, eyes, and mucous membranes from acute exposures to strong water‐soluble acids that can penetrate the skin or those that can volatilize like short‐chain formic, acetic, and propionic acids; dermal sensitization is rare. Saturated ACA are used in a variety of applications, such as in the production of synthetic fiber, resins, plastics, and dyes. Several acids and their esters are important chemical intermediates or solvents and are used in cosmetics or food applications as pH modifiers, preservatives, and antioxidants. Saturated, straight‐chain monocarboxylic acids are metabolized by the β‐oxidation pathway until acetate, propionate, or butyrate are formed which are utilized for energy production via TCA cycle or converted to acetoacetate and subsequently to other ketone bodies, which can be oxidized or excreted in the urine. Propionate originates from odd‐chain acids and is converted to carbohydrates and, unlike acetate, into lipids. This chapter covers 33 ACA their toxicity and workplace exposure limits under a number of regulatory agencies based on the available data.

show abstract

The Metabolism of Ascorbic Acid-1-C14 and Oxalic Acid-C14 in the Rat

Cited by 80 publications

References 24 publications

Manganese-catalyzed Oxidations of 2,3-Diketogulonate^*

Manganese-catalyzed Oxidations of 2,3-Diketogulonate^*

Fluorometric determination of manganese(II) via catalyzed enzymic oxidation of 2,3-diketogulonate

Aliphatic Carboxylic Acids: Saturated

Contact Info

Product

Resources

About

The Metabolism of Ascorbic Acid-1-C14 and Oxalic Acid-C14 in the Rat

Cited by 80 publications

References 24 publications

Manganese-catalyzed Oxidations of 2,3-Diketogulonate*

Manganese-catalyzed Oxidations of 2,3-Diketogulonate*

Fluorometric determination of manganese(II) via catalyzed enzymic oxidation of 2,3-diketogulonate

Aliphatic Carboxylic Acids: Saturated

Contact Info

Product

Resources

About

Manganese-catalyzed Oxidations of 2,3-Diketogulonate^*

Manganese-catalyzed Oxidations of 2,3-Diketogulonate^*