The metabolic syndrome: a cause of sexual dysfunction in women

Esposito, Katherine; Ciotola, Miryam; Marfella, Raffaele; Tommaso, Donato Di; Cobellis, Luigi; Giugliano, Dario

doi:10.1038/sj.ijir.3901310

Cited by 98 publications

(88 citation statements)

References 11 publications

(10 reference statements)

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“…67 Compared with the control group, women with the metabolic syndrome had reduced mean full FSFI score (23.9 ± 5.4 vs 29.9 ± 4.8, Po0.001). We considered the functional results to be good when the FSFI score was 30 or more, intermediate between 23 and 29, and poor below 23.…”

Section: Obesity Metabolic Syndrome and Female Sexual Functionmentioning

confidence: 86%

“…Multivariate analysis found that physical activity, BMI and C-reactive protein independently Figure 3 Individual domains of female sexual function in women with the metabolic syndrome (SM) and in control women. Adapted from Esposito et al 67 Obesity and sexual dysfunction, male and female K Esposito et al predicted IIEF score and almost explained 68% of the variance. This study provided evidence that sustained lifestyle changes can partially ameliorate erectile function in obese men.…”

Section: Lifestyle and Sexual Functionmentioning

confidence: 99%

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Obesity and sexual dysfunction, male and female

et al. 2008

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Obesity has become a worldwide public health problem of epidemic proportions, as it may decrease life expectancy by 7 years at the age of 40 years: excess bodyweight is now the sixth most important risk factor contributing to the overall burden of disease worldwide. Overweight and obesity may increase the risk of erectile dysfunction (ED) by 30-90% as compared with normal weight subjects. On the other hand, subjects with ED tend to be heavier and with a greater waist than subjects without ED, and also are more likely to be hypertensive and hypercholesterolemic. The metabolic syndrome, characterized by a clustering of risk factors associated with insulin resistance and abdominal obesity, associates with ED. Moreover, women with the metabolic syndrome have an increased prevalence of sexual dysfunctions as compared with matched control women. Lifestyle changes aimed at reducing body weight and increasing physical activity induce amelioration of both erectile and endothelial functions in obese men. Moreover, preliminary evidence suggests that a Mediterranean-style diet might be effective in ameliorating sexual function in women with the metabolic syndrome. Lifestyle changes, mainly focussing on regular physical activity and a healthy diet, are effective and safe ways to reduce cardiovascular diseases and premature mortality in all population groups; they may also prevent and treat sexual dysfunctions in both sexes.

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Section: Obesity Metabolic Syndrome and Female Sexual Functionmentioning

confidence: 86%

Section: Lifestyle and Sexual Functionmentioning

confidence: 99%

Obesity and sexual dysfunction, male and female

et al. 2008

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“…Higher BMI can result in a higher intraabdominal pressure and in development and recurrence of urinary incontinence [35]. Lower levels of sexual desire and lower frequency of penile-vaginal intercourse were associated with more body fat and larger waist or hip circumference as well as lower arousal, orgasm, and lubrication, when associated with MetS during the premenopausal state [36,37]. Moreover, sexual pain and orgasmic disorder also occur due to hypoestrogenemia [38].…”

Section: Discussionmentioning

confidence: 99%

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Paolillo

Milan

Paolillo

et al. 2013

Int J Diabetes Dev Ctries

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The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women. Forty five postmenopausal women aged 50 to 60 years were divided into two groups according to fat distribution [waist-to-hip ratio (WHR)]: gynoid group (WHR between 0.68 and 0.8; N=13) and android group (WHR>0.8; N= 32). Body composition, skinfold thickness, serum/plasma estradiol, creatinine, urea, lipid profile, glucose and insulin, maximal exercise testing and menopause rating scale (MRS) were evaluated. The android group when compared to the gynoid group showed (P<0.05): (i) higher values of body mass, BMI, waist circumference, body fat, lean mass and skinfold thickness; (ii) higher values of estradiol, triglycerides, very low-density lipoprotein (VLDL) and insulin levels with lower insulin sensitivity (%S) and greater insulin resistance (%IR) index; (iii) higher blood pressure (BP) during rest and lower maximal heart rate (HRmax) during maximal exercise testing and; (iv) higher scores of the somatic and urogenital-sexual symptoms. This study suggests that android postmenopausal women develop features that can lead to metabolic syndrome (MetS) and future cardiovascular disease (CVD), and these women may present higher scores of somatic and urogenital-sexual symptoms.

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“…Los factores asociados a la disfunción sexual han sido estudiados por varios autores, registrando el síndrome metabólico como un factor de riesgo independiente (16)(17)(18), la edad, el grado de instrucción, la salud física (19,20) y mental en la mujer (21), aunque otros autores refieren además el estado civil casado, hábito de fumar (22), así como tener más de 14 años de matrimonio, más de 2 hijos, el grado de instrucción, el tener una pareja mayor de 42 años (23) y el uso de terapia antidepresiva (24).…”

Section: Introductionunclassified

“…Results: 342 women (114 cases / 228 controls) participated, with a mean age of 40.5 ± 9.2 and a BMI of 25.2 ± 3.5; 45.9% (157) are married; 53.5% (183) with secondary level, 41.5% (142) housewives, 17.8% (61) menopausal, 34.8% (119) with metabolic syndrome. In addition, with chronic disease, 32.7% (112), anxiety 16.4% (56), depression 5% (17), drug consumption 35.1% (72). In the bivariate analysis, the factors of widowhood, retired occupation, 2 previous pregnancies, ill health, chronic illness, smoking, anxiety and depression, and as a protective factor, married marital status and higher educational level as associated factors.…”

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confidence: 99%

Factores asociados a disfunción sexual en mujeres atendidas en un hospital nivel III-Chiclayo-Perú

Díaz-Vélez

Samalvides-Cuba

2017

Rev. chil. obstet. ginecol.

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386 Trabajos OriginalesFactores asociados a disfunción sexual en mujeres atendidas en un hospital nivel III-Chiclayo-Perú Associated factors in women's sexual dysfunction in a hospital level attended III-Chiclayo -Peru RESUMENObjetivo: Identificar los factores asociados a la disfunción sexual en las mujeres atendidas en un hospital nivel III. Material y Método: estudio de casos y controles emparejados por edad e índice de masa corporal, realizada en mujeres de 18-59 años que acuden a consultorio externo. Se usó el Índice de Función Sexual Femenina para definir caso (≥24 puntos) y control (<24 puntos), y los factores a evaluar fueron síndrome metabólico definida según International Diabetes Federation (IDF), ansiedad y depresión mediante test validados; menopausia, alcohol, fumar, situación de salud, estado civil, grado de instrucción, ocupación, número de embarazos. Resultados: participaron 342 mujeres (114 casos/228 controles), con edad promedio de 40,5±9,2 e IMC de 25,2±3,5; 45,9% (157) son casadas; 53,5% (183) con nivel secundaria, 41,5% (142) amas de casa, 17,8% (61) menopaúsicas, 34,8% (119) con síndrome metabólico. Además, con enfermedad crónica 32,7% (112), ansiedad 16,4% (56), depresión 5% (17), consumo de medicamentos 35,1% (72). En el análisis bivariado los factores estado civil viuda, ocupación jubilada, 2 embarazos previos, estado de salud enferma, enfermedad crónica, fumar, ansiedad y depresión, y como factor protector, el estado civil casada y nivel de instrucción superior como factores asociados. En el análisis multivariado realizada con regresión logística, se obtuvieron como factores asociados al estado civil casada 0,58 (IC95%: 0,33-0,87), conviviente 8,11 (IC95%: 2,36-17,84), fumar 2,26 (IC95%: 1,08-4,76), ansiedad 1,21 (IC95%: 1,10-1,45) y estado de salud enfermo 1,50 (IC95%: 1,26-1,94). Conclusiones: la disfunción sexual femenina está asociada con estado civil casada/conviviente, ansiedad, estado de salud y fumar.PALABRAS CLAVE: disfunción sexual, síndrome metabólico, calidad de vida. ABSTRACTObjective: To identify the factors associated with sexual dysfunction in women treated at a level III hospital. Material and Method: case-control study matched by age and body mass index, performed in women aged 18-59 years who attend an outpatient clinic. The Female Sexual Function Index was used to define case (≥24 points) and control (<24 points), and the factors to be evaluated were International Diabetes Federation (IDF) -

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The metabolic syndrome: a cause of sexual dysfunction in women

Cited by 98 publications

References 11 publications

Obesity and sexual dysfunction, male and female

Obesity and sexual dysfunction, male and female

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Factores asociados a disfunción sexual en mujeres atendidas en un hospital nivel III-Chiclayo-Perú

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