The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Hou, Qingtao; Li, Yun; Li, Ling; Cheng, Gaiping; Sun, Xin; Li, Sheyu; Tian, Haoming

doi:10.3390/nu7125536

Cited by 81 publications

(56 citation statements)

References 52 publications

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“…< 200 mg/dl was higher in intervention arm, 19 out of 36 (52.8%) subjects as against control arm, where 12 out of 33 subjects (36.4%) had total cholesterol levels within the normal range. It has been observed that oats may be beneficial for insulin sensitivity and glycemic parameters, thus controlling serum triglycerides [27]. These actions may have resulted in stable serum triglyceride levels in the oats group vs. non-significant slight increase in the control group.…”

Section: Discussionmentioning

confidence: 99%

Effects of 3 g of soluble fiber from oats on lipid levels of Asian Indians - a randomized controlled, parallel arm study

2017

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BackgroundCardiovascular diseases are more prevalent and severe in Asian Indians. Simple diet-based strategies are important for prevention of cardiovascular diseases.The aim of the present study was to evaluate the effects of oats consumption on lipid parameters in mildly hypercholesterolemic Asian Indians living in India.MethodsA short-term, prospective, open-labeled, randomized controlled, parallel group study was conducted. Mildly hypercholesterolemic (total cholesterol >200 mg/dL and <240 mg/dL) subjects (n = 80) were randomized into two groups: intervention (n = 40) and usual diet (n = 40). Sample size was calculated for a two-group parallel superiority randomized control trial. Out of 80 enrolled subjects 69 subjects completed the study; 33 in the control group and 36 in the intervention group. In the intervention group, patients were served 70 g of oats twice a day in the form of porridge and upma (A thick porridge from oats with seasonings and vegetables) under observation at the study site. Lipid parameters were assessed at baseline and after 4 weeks of intervention.ResultsThere was a reduction of 3.1% in total cholesterol levels in the control group as against 8.1% reduction in the intervention group (p < 0.02). Greater reductions were also seen in low-density lipoprotein cholesterol in the intervention group (11.6%) as compared to control group (4.1%, p < 0.04) over a period of 28 days.ConclusionDaily consumption of 3 g of soluble fiber from 70 g of oats leads to beneficial effects on the lipid parameters, specifically total cholesterol and low-density lipoprotein cholesterol in hypercholesterolemic Asian Indians. Large scale studies over a longer period of intervention are required to further establish the cholesterol-lowering effect of oat fiber.Trial registrationThe study was retrospectively registered at clinicaltrials.gov (dated: 25th Februrary.2015) with registration number NCT02376660.

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Section: Discussionmentioning

confidence: 99%

Effects of 3 g of soluble fiber from oats on lipid levels of Asian Indians - a randomized controlled, parallel arm study

2017

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“…In recent studies, Ho et al (2016a), Yanai et al (2018), and Hou et al (2015) showed a significant association between dietary fiber intake and reduction of LDL-C. However, these studies did not found a significant effect of fiber on highdensity cholesterol (HDL)-C (Table 1).…”

Section: Functionsmentioning

confidence: 98%

Recent progress in the use of functional foods for older adults: A narrative review

Jędrusek‐Golińska

Górecka

Buchowski

et al. 2020

Comp Rev Food Sci Food Safe

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The number and proportion of older adults are increasing globally, and it is predicted that in 2020, there will be 723 million people worldwide aged 66 and older. In recent decades, numerous studies showed that healthy eating is positively associated with better nutritional status and quality of life, and the decreased incidence of noncommunicable diseases. As older adults become health conscious, the demand for foods and beverages rich in nutrients and bioactive compounds has increased. The increased demand for healthy food stimulated a recent rapid increase in designing, producing, and marketing functional foods to prevent or correct nutrient deficiencies and to improve the nutritional status of older adults. These functional products contain and/or are enriched with dietary fiber; omega‐3 polyunsaturated fatty acids; phytoestrogens; polyphenols; carotenoids such as alpha‐ and beta‐carotene; lutein and zeaxanthin; pre‐, pro‐, and synbiotics; and plant sterols and stanols. A limited number of publications have thoroughly addressed the effect of functional foods on the nutritional status of older adults. The goal of this review was to review existing recent research on the role of functional foods in healthy and active aging.

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“…Auch in einer weiteren Studie, in der der Effekt derartiger Hafertage mit einer isokalorischen Diät verglichen wurde, fanden sich erneut eine deutliche Reduktion der Insulindosis sowie eine Verbesserung der HbA 1c -Werte im Vergleich zur Kontrolldiät [23]. In einer Metaanalyse von insgesamt 16 Studien zur Auswirkung haferbasierter Diäten zeigte sich eine mittlere Reduktion der HbA 1c -Werte um 0,42 % ebenso wie eine Verbesserung der Nüchtern-und postprandialen Blutzuckerwerte sowie der Lipidwerte [24].…”

Section: Stationäre Interventionsmöglichkeiten Beim Typ-2-diabetesunclassified

Stationäre Therapie des Typ-2-Diabetes

Meier

2020

Diabetologie und Stoffwechsel

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ZusammenfassungDer überwiegende Teil der Patienten mit Typ-2-Diabetes kann im ambulanten Umfeld (Hausarztpraxen und Diabetes-Schwerpunktpraxen) adäquat und kosteneffektiv behandelt werden. Dennoch erreichen trotz guter ambulanter Versorgungsstrukturen ca. 20–30 % der Patienten keine zufriedenstellende Blutzuckereinstellung. In derartigen Fällen kann eine stationäre Diabetesbehandlung sinnvoll sein. Die Indikationen für eine stationäre Diabetesbehandlung sind in der Nationalen Versorgungsleitlinie Diabetes dargelegt. Besondere Elemente einer stationären Diabetesbehandlung können neben spezifischen Ernährungsinterventionen (z. B. Entlastungstage) spezialisierte Schulungsprogramme, individualisierte Bewegungstherapie ebenso wie eine Anpassung der Insulintherapie bis hin zur intravenösen Insulinbehandlung sein. Eine psychosomatische Mitbetreuung der Patienten erscheint in einer spezialisierten Diabetesbehandlungseinrichtung von essenzieller Bedeutung. Durch die Kombination aus derartigen intensiven Therapiestrategien, einer praktischen Anleitung zur Lebensstilintervention und gruppendynamischen Effekten kann bei vielen Patienten im stationären Rahmen eine deutliche und nachhaltige Verbesserung der Blutzuckereinstellung erzielt werden. Leider ist der Fortbestand derartiger Behandlungseinrichtungen durch die zunehmende Ökonomisierung im Gesundheitssystem und den politisch forcierten Abbau stationärer Versorgungsstrukturen akut gefährdet.

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The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Cited by 81 publications

References 52 publications

Effects of 3 g of soluble fiber from oats on lipid levels of Asian Indians - a randomized controlled, parallel arm study

Effects of 3 g of soluble fiber from oats on lipid levels of Asian Indians - a randomized controlled, parallel arm study

Recent progress in the use of functional foods for older adults: A narrative review

Stationäre Therapie des Typ-2-Diabetes

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