The Menopause: A Signal for the Future

Speroff, Leon; Barnhart, Kurt T.; González, Josué M.

doi:10.1016/b978-012369443-0/50002-8

Cited by 15 publications

(19 citation statements)

References 112 publications

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“…Hot flushes are sudden and transient feelings of generalized heat, especially in the chest, face, head and neck, and are followed by large amounts of sweating. This phenomenon usually occurs at night, consequently leading to insomnia (Speroff, 1999).…”

Section: Physiological Changes Affecting Quality Of Sleepmentioning

confidence: 99%

Exploring Quality of Sleep and Its Related Factors Among Menopausal Women

Hsu

Lin

2005

Journal of Nursing Research

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Sleep, a basic physiological need of all humans, appears to be both integrative and restorative. However, studies have reported that 33-51% of women show a dramatic increase in sleep disturbance in the mid-life years, a time when they enter menopause. The purposes of this study were to (1) explore the prevalence of poor sleep quality in menopausal women; (2) identify the relationship between sleep quality of menopausal women and its related factors; (3) predict the possible explanations of how the related variables affect sleep quality of menopausal women; and (4) provide recommendations for future strategies that aim to improve sleep quality of menopausal women. A cross-sectional, correlation coefficient design was used. Purposive sampling was employed to recruit 197 menopause women from a small town in central Taiwan. T-test, one-way ANOVA, and multiple regression were used for data analysis. The results were as follows: (1) overall, the total score for sleep quality was 5.55 ± 3.47; 57.9% of subjects were identified as good sleepers and 42.1% as poor sleepers; (2) there were significant differences in quality of sleep related to occupational situation, history of chronic disease, menopausal status, number of chronic diseases, and number of menopausal symptoms (t = -3.49, -3.37, p < .01; F = 3.62, p < .05, F = 4.95, 5.35, p < .01); (3) depression and aging were strongly related to quality of sleep (r = .57; .22, p < .01); (4) 36% of variance in quality of sleep can be explained by depression and aging.

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Section: Physiological Changes Affecting Quality Of Sleepmentioning

confidence: 99%

Exploring Quality of Sleep and Its Related Factors Among Menopausal Women

Hsu

Lin

2005

Journal of Nursing Research

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“…This period, according to the World Health Organization, commonly occurs between the ages of 40 and 65. It is closely related to loss of activity of ovarian follicles, with consequent estrogen deficiency 1,2 . Approximately 70% of women repor t some type of symptom during the climacteric period.…”

Section: Introductionmentioning

confidence: 99%

“…The most common complaints are vasomotor symptoms and night sweats. In addition, vaginal dr yness, dyspareunia and urinar y urgency, which are associated with urogenital atrophy, may inter fere with the sex life and quality of life of postmenopausal women 2,3 . Some women also experience cognitive impairment, insomnia, depression, irritability, fatigue, psychological symptoms, and increased risk for osteoporosis and cardiovascular disease 3,4 .…”

Section: Introductionmentioning

confidence: 99%

Efeitos do Trifolium pratense nos sintomas climatéricos e sexuais na pós-menopausa

Giorno¹,

Fonseca²,

Bagnoli³

et al. 2010

Rev. Assoc. Med. Bras.

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objectIve. To evaluate the effects of treatment with Trifolium pratense on climacteric symptoms and sexual satisfaction in postmenopausal women. Methods. This is a prospective, randomized, double-blind, placebo-controlled study. Initially, 120 women aged 45-65 years with menopausal symptoms, more than 12-month amenorrhea and no treatment in the past six months were selected. The participants were then divided into two groups: TG -receiving 40 mg Trifolium pratense, 1 capsule/day; PG -receiving placebo capsules containing lactose (control), 1 capsule/day. The duration of treatment was 12 months. The patients underwent clinical and laboratory evaluation before treatment and at four, eight and 12 months of treatment. The Kupperman Menopausal Index and the Golombok Rust Inventory of Sexual Satisfaction (GRISS) were used. At the end of the study, each group comprised 50 patients. results. According to the Kupperman Menopausal Index, there was significant improvement in menopausal symptoms after four months of treatment, especially in relation to hot flashes, when compared to baseline data in both groups. However, no significant differences were observed between groups. There was no improvement in sexual satisfaction after treatment. conclusIon. A 12-month treatment with a daily dose of 40 mg Trifolium pratense did not yield a significant improvement in menopausal symptoms and sexual satisfaction.

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“…The most common symptoms are vasomotor symptoms, night sweats, cognitive impairment, insomnia, depression, irritability, fatigue, psychological symptoms, and incre ased risk for osteoporosis and cardiovascular disease (1,3). In addition, vaginal dryness, dyspareunia, and urinary urgency, which are related to urogenital atrophy, may negatively affect the sex life and quality of life of postmenopausal women (2,4). Previous studies have suggested that the potential risk of metabolic diseases, including obesity, heart disease, diabetes and hypertension, are increased in the postmenopausal state (5,6).…”

Section: Introductionmentioning

confidence: 99%

“…This period is associated with the loss of activity of the ovarian follicles, with consequent estrogen deficiency (2).…”

Section: Introductionmentioning

confidence: 99%

Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice

Kang¹,

Choi²,

Kim³

et al. 2017

Experimental and Therapeutic Medicine

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Abstract. In the present study, the complex anti-climacterium potential of standardized pomegranate concentrated solution (PCS) was investigated using bilateral ovariectomy (OVX) female ddY mice. Changes in body weight and gain during experimental periods, food consumption, serum estradiol levels, total body and abdominal fat densities, abdominal fat pads, and uterus weights were observed, along with the histopathology of abdominal fat pads and uterus for anti-obesity and estrogenic effects. In addition, liver weights, serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels, and histopathological inspections were performed to explore the hepato-protective effects. Serum total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein, and triglyceride (TG) levels were monitored for hypolipidemic effects with total body and femur mean bone mineral density (BMD), right femur wet, dry and ash weights, strength, serum osteocalcin, bone-specific alkaline phosphatase (bALP) contents, and histological and histomorphometrical analyses for anti-osteoporosis activity. As a result of OVX, notable increases in body weight and gains, food consumption, abdominal fat mass densities, weights of abdominal fat pads deposited in the abdominal cavity, and serum AST, ALT, TC, LDL, TG, and osteocalcin levels were observed, along with decreases in the uterus, liver, and femur weights, mean total body and femur BMD, femur strength, serum bALP, and estradiol levels. In addition, marked hypertrophic alterations in adipocytes located in the deposited abdominal fat pads, liver steatosis, uterine disused atrophic changes, and decreases in bone mass and structures of the femur were also observed in OVX control mice with significant increases in bone resorption markers based on histopathological and histomorphometrical analysis. However, these estrogen-deficient climacterium symptoms were significantly (P<0.05 or P<0.01) inhibited after 84 days of continuous treatment with estradiol and PCS (1, 2 and 4 ml/kg), respectively. The present results suggested that PCS was able to effectively inhibit or refine the climacterium symptoms, including obesity, hyperlipidemia, hepatic steatosis, and osteoporosis, induced by OVX in ddY mice.

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The Menopause: A Signal for the Future

Cited by 15 publications

References 112 publications

Exploring Quality of Sleep and Its Related Factors Among Menopausal Women

Exploring Quality of Sleep and Its Related Factors Among Menopausal Women

Efeitos do Trifolium pratense nos sintomas climatéricos e sexuais na pós-menopausa

Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice

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