The memory ameliorating effects of novel N-benzyl pyridine-2-one derivatives on scopolamine-induced cognitive deficits in mice
Swati Pant,
Mohan Gupta,
Tulika Anthwal
et al.
Abstract:Background
Alzheimer's disease (AD), the most common form of progressive dementia in the elderly, is a chronic neurological disorder that decreases cognitive ability. Although the underlying cause of AD is yet unknown, oxidative stress and brain acetylcholine shortage are the key pathogenic causes.
Results
The current study shows that these derivatives have the potential to improve memory in mice by inhibiting scopolamine-induced acetylcholinestera… Show more
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