The medicinal uses of Callicarpa L. in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review

Yanhua, Tu; Sun, Lianna; Guo, Meili; Chen, Wansheng

doi:10.1016/j.jep.2012.12.051

Cited by 60 publications

(34 citation statements)

References 31 publications

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“…Callicarpae macrophyllae folium is reported to be used in TCM tradition for bleedings, hematoptysis, and hematemesis [ 26 ]. Anti-inflammatory, antimicrobial, and analgesic effects of Callicarpae macrophyllae folium are reported but not yet fully investigated [ 73 ].…”

Section: Herbal Combinationsmentioning

confidence: 99%

A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-Induced Oral Mucositis

Meyer-Hamme

Beckmann

Radtke

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Oral mucositis is one of the common side effects of chemotherapy treatment with potentially severe implications. Despite several treatment approaches by conventional and complementary western medicine, the therapeutic outcome is often not satisfactory. Traditional Chinese Medicine (TCM) offers empirical herbal formulas for the treatment of oral ulceration which are used in adaptation to chemotherapy-induced mucositis. While standard concepts for TCM treatment do not exist and acceptance by conventional oncologists is still low, we conducted a review to examine the evidence of Chinese herbal treatment in oral mucositis. Eighteen relevant studies on 4 single herbs, 2 combinations of 2 herbs, and 11 multiherbal prescriptions involving 3 or more compounds were included. Corresponding molecular mechanisms were investigated. The knowledge about detailed herbal mechanisms, especially in multi-herbal prescriptions is still limited. The quality of clinical trials needs further improvement. Meta-analysis on the existent database is not possible but molecular findings on Chinese medicinal herbs indicate that further research is still promising for the treatment of chemotherapy-induced oral mucositis.

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Section: Herbal Combinationsmentioning

confidence: 99%

A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-Induced Oral Mucositis

Meyer-Hamme

Beckmann

Radtke

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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“…is native to western and central China [3], Vietnam, Laos, Cambodia, and Thailand [4]. The plant is used in traditional Chinese medicine to treat hematemesis (oral decoction of the leaves) and to treat wounds and bruises (fresh leaves externally) [5]. Flavonoids, sterols, triterpenoids [2], and diterpenoids [6] have been characterized in the leaves of C. bodinieri.…”

Section: Introductionmentioning

confidence: 99%

Callicarpa Species from Central Vietnam: Essential Oil Compositions and Mosquito Larvicidal Activities

Hùng

Hương

Chung

et al. 2020

Plants

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There are around 140 species in the genus Callicarpa, with 23 species occurring in Vietnam. The Vietnamese Callicarpa species have been poorly studied. In this work, the leaf essential oils of C. bodinieri, C. candicans, C. formosana, C. longifolia, C. nudiflora, C. petelotii, C. rubella, and C. sinuata, have been obtained from plants growing in central Vietnam. The chemical compositions of the essential oils were determined using gas chromatography – mass spectrometry. Mosquito larvicidal activities of the essential oils were carried out against Aedes aegypti. All of the Callicarpa leaf essential oils showed larvicidal activity, but two samples of C. candicans were particularly active with 48-h LC50 values of 2.1 and 3.8 μg/mL. Callicarpa candicans essential oil should be considered as a potential alternative mosquito control agent.

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“…Interestingly, Callicarpa species are also a key component of Asian traditional medicines (Tu et al, 2013). C. arborea Roxb.…”

Section: Introductionmentioning

confidence: 99%

Growth Inhibitory Activity of Callicarpa americana Leaf Extracts Against Cutibacterium acnes

et al. 2019

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Acne vulgaris is a common skin disease affecting adolescents and young adults of all ethnic groups, negatively impacting self-esteem, self-confidence, and social life. The Gram-positive bacteria Cutibacterium acnes colonizes the sebum-rich follicle and contributes to inflammation of the pilosebaceous gland. Long-term antibiotic therapies targeting C. acnes lead to the development of antimicrobial resistance, and novel acne vulgaris therapies are needed. This study investigated the C. acnes inhibitory activity of Callicarpa americana leaves, a native Southeastern United States shrub historically used by Native Americans to treat fever, stomachache, and pruritis. Flash chromatography fractions of the ethyl acetate-soluble C. americana ethanol leaf extract (649C-F9 and 649C-F13) exhibited MICs ranging from 16 to 32 µg ml−1 and IC50 range of 4–32 μg ml−1 against a panel of 10 distinct C. acnes isolates. Cytotoxicity against an immortalized human keratinocyte cell line (HaCaTs) skin was detected at more than eight times the dose required for growth inhibitory activity (IC50 of 256 μg ml−1 for 649C-F9 and IC50 of >512 μg ml−1 for 649C-F13). This work highlights the potential of C. americana leaf extracts as a cosmeceutical ingredient for the management of acne vulgaris. Further research is necessary to assess its mechanism of action and in vivo efficacy.

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The medicinal uses of Callicarpa L. in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review

Cited by 60 publications

References 31 publications

A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-Induced Oral Mucositis

A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-Induced Oral Mucositis

Callicarpa Species from Central Vietnam: Essential Oil Compositions and Mosquito Larvicidal Activities

Growth Inhibitory Activity of Callicarpa americana Leaf Extracts Against Cutibacterium acnes

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