The mechanism underlying the functionalisation of cobalt nanoparticles by carboxylic acids: a first-principles computational study

Farkaš, Barbara; Terranova, Umberto; Leeuw, Nora H. de

doi:10.1039/d0tb02928a

Cited by 6 publications

(4 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cobalt nanoparticles hold immense potential across diverse applications, including fuel cells, catalysis, medicine, microelectronics, targeted therapies, and drug delivery. − The magnetic properties of cobalt nanostructures are of particular significance and are paving the way for innovative approaches to utilizing nanoparticles in targeted drug delivery systems. , Furthermore, due to their unique physicochemical characteristics, cobalt nanoparticles are promising candidates for sensing various chemicals . However, previous research has focused on cobalt resistance. − Studies on the microbial production of cobalt oxide nanoparticles remain limited.…”

Section: Introductionmentioning

confidence: 99%

“… 6 − 9 The magnetic properties of cobalt nanostructures are of particular significance and are paving the way for innovative approaches to utilizing nanoparticles in targeted drug delivery systems. 10 , 11 Furthermore, due to their unique physicochemical characteristics, cobalt nanoparticles are promising candidates for sensing various chemicals. 12 However, previous research has focused on cobalt resistance.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cobalt Oxide Nanoparticle Synthesis by Cell-Surface-Engineered Recombinant Escherichia coli and Potential Application for Anticancer Treatment

Kumaravel,

Sengupta,

Sathiyamoorthy

et al. 2024

ACS Omega

View full text Add to dashboard Cite

Cell surface display engineering facilitated the development of a cobalt-binding hybrid Escherichia coli. OmpC served as the molecular anchor for showcasing the cobalt-binding peptides (CBPs), creating the structural model of the hybrid OmpC− CBPs (OmpC−CP, OmpC−CF). Subsequently, the recombinant peptide's cobalt adsorption and retrieval effectiveness were evaluated at various concentrations. When subjected to a pH of 7 and a concentration of 2 mM, OmpC−CF exhibited a significantly higher cobalt recovery rate (2183.87 mol/g DCW) than OmpC−CP. The strain with bioadsorbed cobalt underwent thermal treatment at varying temperatures (400 °C, 500 °C, 600 °C, and 700 °C) and morphological characterization of the thermally decomposed cobalt nanoparticle oxides using diverse spectroscopy techniques. The analysis showed that nanoparticles confined themselves to metal ions, and EDS mapping detected the presence of cobalt on the cell surface. Finally, the nanoparticles' anticancer potential was assessed by subjecting them to heating at 500 °C in a furnace; they demonstrated noteworthy cytotoxicity, as evidenced by IC 50 values of 59 μg/mL. These findings suggest that these nanoparticles hold promise as potential anticancer agents. Overall, this study successfully engineered a recombinant E. coli capable of efficiently binding to cobalt, producing nanoparticles with anticancer properties. The results of this investigation could have significant implications for advancing novel cancer therapies.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cobalt Oxide Nanoparticle Synthesis by Cell-Surface-Engineered Recombinant Escherichia coli and Potential Application for Anticancer Treatment

Kumaravel,

Sengupta,

Sathiyamoorthy

et al. 2024

ACS Omega

View full text Add to dashboard Cite

show abstract

“…Although the mechanism of free PAA polymerization has been extensively studied, [17][18][19][20] limited research is available on polymerization mechanism for coating nanomaterials with a monolayer of carboxyl groups that does not compromise the magnetic properties of IONPs. 21,22 Hence, this work aims to investigate the inuence of the amounts of acrylic acid (AA), IONPs and sodium dodecyl sulfate (SDS) on the physical properties of PAA-IONPs. The ndings are then correlated to the performance of the beads for DNA extraction and size selection under various conditions.…”

Section: Introductionmentioning

confidence: 99%

Optimized synthesis of polyacrylic acid-coated magnetic nanoparticles for high-efficiency DNA isolation and size selection

Bali,

Brennhaug,

Bjørås

et al. 2023

RSC Adv.

View full text Add to dashboard Cite

show abstract

“…The unique feature of CoNPs being magnetic makes them ideal candidates for targeted drug delivery [16,17]. Coupled with their small size and physicochemical properties, CoNPs qualify for use in sensors for detection of various substances [18].…”

Section: Introductionmentioning

confidence: 99%

THE CHEMICAL SYNTHESIS AND CHARACTERIZATION OF COBALT (Co), NICKEL (Ni) AND COPPER (Cu) NITROGEN-DOPED GRAPHENE NANOCOMPOSITES

Shuaibu¹,

Audu²

2022

JCSN

View full text Add to dashboard Cite

Nitrogen-doped graphene (NGr) and metal nitrogen-doped graphene nanocomposites (MNGr) were synthesized employing chemical reduction method. The synthesized nanocomposites and graphene oxide (GO) were characterized via conventional characterization techniques. UV-Vis spectra of the synthesized metal nanocomposites indicated that cobalt (Co), nickel (Ni) and (Cu) copper nanoparticles (NPs) exhibited surface plasmon resonance peaks at 515 nm, 230 nm and 770 nm respectively, indicating the formation of the respective metal nanoparticles (MNPs) on NGr. The EDXRF analysis showed that the synthesized nanocomposites of the metals are very pure. SEM indicated the appearance of wrinkles and crumples, confirming the structural morphology of NGr. It also showed the attachment of smaller and white spherically shaped spots with insubstantial aggregation of MNPs on NGr. FTIR analysis showed the C=C stretching frequency in the GO that has shifted to a higher wavenumber from 1632.6-1640 cm- 1, indicating successful reduction of the nanocomposites. XRD analysis revealed the presence of the face-centred cubic crystalline lattices (fcc) for Ni, Co and Cu nanoparticles. The Scherrer equation was used to calculate the mean particle sizes of the MNPs formed on the NGr support.

show abstract

The mechanism underlying the functionalisation of cobalt nanoparticles by carboxylic acids: a first-principles computational study

Abstract: The promise of biocompatible magnetic nanoparticles with high magnetic saturation for implementation as drug carriers and hyperthermia agents has generated significant interest in functionalised cobalt nanoparticles. Carboxylic acid coatings on...

Cited by 6 publications

References 92 publications

Cobalt Oxide Nanoparticle Synthesis by Cell-Surface-Engineered Recombinant Escherichia coli and Potential Application for Anticancer Treatment

Cobalt Oxide Nanoparticle Synthesis by Cell-Surface-Engineered Recombinant Escherichia coli and Potential Application for Anticancer Treatment

Optimized synthesis of polyacrylic acid-coated magnetic nanoparticles for high-efficiency DNA isolation and size selection

THE CHEMICAL SYNTHESIS AND CHARACTERIZATION OF COBALT (Co), NICKEL (Ni) AND COPPER (Cu) NITROGEN-DOPED GRAPHENE NANOCOMPOSITES

Contact Info

Product

Resources

About