The mechanism of oxidation of NADH analogues 4. Photooxidation of N-acetyl-substituted 1,4-dihydropyridine in the presence of quinones

Photo‐CIDNP Study of the Interaction of Tyrosine with Nifedipine. An Attempt to Model the Binding Between Calcium Receptor and Calcium Antagonist Nifedipine¶

“…This is also corroborated by the polarization effects in the aromatic region (Fig. 2) detected for the 4′,6′‐H, which is in agreement with the HFI distribution in this radical ( 17 ).…”

Recent developments in the chemistry of dihydropyridines

“…83 Photoinduced oxidations of Hantzsch 1,4-dihydropyridines have been performed through SET processes with CCl 4 , 103 and quinones. 104 Electrochemical oxidation of 4-(pyridinium-3-yl)-1,4-dihydropyridines and 1,2-dihydropyridines (arising from [3 ϩ 2] cycloadditions) affords the aromatized compounds; occasional cyclizations at the 4-substituent to yield indolizines have also been reported. 105 Remarkable oxidations of enantiomerically pure Hantzsch-type dihydropyridines have allowed the enantioselective synthesis of atropoisomeric γ-arylpyridines; in this way NOBF 4 reacts with dihydropyridine (S )-59 to yield pyridine (R)-60 (95% ee), whereas MnO 2 or TEMPO ϩ -BF 4…”

Antioxidant Activity of Deferasirox and Its Metal Complexes in Model Systems of Oxidative Damage: Comparison with Deferiprone

“…The reaction was initiated by the addition of the metal salt into the sample. Dihydropyridines are quite sensitive to external influences, such as light [ 76 ], therefore samples were incubated at a temperature of 278 K and in the absence of light in order to minimize the effect of DHP autoxidation. The 1 H-NMR spectra were also recorded using a Bruker AVHD-500 spectrometer (500 MHz).…”