“…He noted the pronounced dilation of the right heart and he attributed this to cardiac failure. Coca in 1919 [46], and Drinker and Bronfenbrenner in 1924, observed an increase in pulmonary arterial pressure in the rabbit beginning within 30 seconds of antigenic challenge. Coca observed a greatly increased resistance to perfusion of saline through the pulmonary artery during anaphylaxis in rabbits and inferred that the right heart dilatation was secondary to the '.…”
Section: Early Studies On the Pathophysiology Of Anaphylaxismentioning
“…He noted the pronounced dilation of the right heart and he attributed this to cardiac failure. Coca in 1919 [46], and Drinker and Bronfenbrenner in 1924, observed an increase in pulmonary arterial pressure in the rabbit beginning within 30 seconds of antigenic challenge. Coca observed a greatly increased resistance to perfusion of saline through the pulmonary artery during anaphylaxis in rabbits and inferred that the right heart dilatation was secondary to the '.…”
Section: Early Studies On the Pathophysiology Of Anaphylaxismentioning
“…A l'autopsie, congestion importante des viscères abdominaux et de la circulation de retour: turgescence du coeur droit et de l'artère pulmonaire, traduisant la présence d'un obstacle à la pro gression du sang dans la petite circulation (Coca, 1919). c) Asphyxie par bronchospasme: cobaye Le choc anaphylactique se caractérise par l'apparition rapide d'une dyspnée de type expiratoire, qui entraîne l'asphyxie.…”
Section: Réactions Anaphylactiques Générales Entraînant La Mort Deunclassified
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