The Mechanics of the Respiratory System During Anesthesia

Don, H. F.; Robson, John

doi:10.1097/00000542-196503000-00007

Cited by 76 publications

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“…There are conflicting reports on the effects of atropine on R AW during anaesthesia. Don and Robson (1965) reported that total flow resistance in patients anaesthetized with nitrous oxide was decreased by 33% following atropine in the same dosage as was used in our study. On the other hand, Brakensiek and Bergman (1970) reported that atropine 0.8 mg i.v.…”

Section: Resultssupporting

confidence: 58%

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Atropine Reversal of Hypercarbia during Enflurane Anaesthesia

Wahba¹,

Sadkova²

1979

Survey of Anesthesiology

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SUMMARYAtropine was given i.v. to 35 spontaneously breathing healthy adults anaesthetized with enflurane to determine if it would reduce Paco, by improving gas exchange. Five minutes after administration of atropine, P^co, decreased from mean 7.18 to 6.65 kPa ( -7%), while mean 9?. increased from 4.8 to 6.1 litre min" 1 ( + 27%). These changes were maintained 15 min later in the 20 patients studied at that time. Older and more obese patients showed a more significant change. Respiratory frequency and Pao, did not alter.During a study of the pattern of breathing during enflurane anaesthesia, we found that there was a relationship between the forced expiratory volume in one second (FEV^o) and Pa C02 . The increase in Fa COa during anaesthesia compared with the value before anaesthesia correlated with the ratio FEV 1 . 0 / vital capacity* while the values during anaesthesia correlated with the ratio FEV 1 . 0 /height.f We suggested that airway resistance (-RAW) mav influence the increase in Pa cc , 2 occurring under general anaesthesia with spontaneous ventilation. If this is so, a reduction in i? AW should improve pulmonary ventilation. The present study was designed to test this hypothesis by measuring expired minute volumes (VE) and arterial blood-gas tensions before and after the i.v. administration of atropine in 35 healthy adult patients undergoing minor peripheral surgery. Atropine was chosen because its effects on flow resistance have been measured by Don and Robson (1965). METHODSThirty-five healthy adults undergoing elective operations on the periphery of the body gave consent for the study, which was approved by the Hospital o, (kPa) = 10.08-0.08 (r = 0.6 P< 0.01). t Paco, (kPa) = 9.17-1.2 FEV^o/height (m) (r = 0.65 P< 0.001).

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Section: Resultssupporting

confidence: 58%

“…administration of atropine in 35 healthy adult patients undergoing minor peripheral surgery. Atropine was chosen because its effects on flow resistance have been measured by Don and Robson (1965). …”

mentioning

confidence: 99%

Atropine Reversal of Hypercarbia during Enflurane Anaesthesia

Wahba¹,

Sadkova²

1979

Survey of Anesthesiology

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“…Dentre estes, o MOFI com fluxo constante tem sido o mais utilizado. O MOFI é fundamentado no desenvolvimento teórico proposto por Bates e col. 58,59 , baseado nos trabalhos pioneiros de Don e Robson, Rattenborg e Holaday 60,61 . A partir destes estudos pode-se descrever o sistema respiratório como sendo constituído de múltiplos compartimentos, ligados em paralelo, cada qual com diferentes tempos de esvaziamento, definidos como constantes de tempo.…”

Section: O Método Do Balão Esofágicounclassified

A importância da pressão pleural na avaliação da mecânica respiratória

Fernandes¹

2006

Rev. Bras. Anestesiol.

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“…Pulmonary mechanics General anesthesia is consistently marked by an impairment in lung volumes (3)(4)(5) and lung compliance (6). Pulmonary mechanics General anesthesia is consistently marked by an impairment in lung volumes (3)(4)(5) and lung compliance (6).…”

Section: A Lung Function Changes Induced Bymentioning

confidence: 99%

Lung function during anesthesia and respiratory insufficiency in the postoperative period: physiological and clinical implications

Schwieger

Gamulin

Suter

1989

Acta Anaesthesiol Scand

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This review covers the physiological and clinical implications of lung function during anesthesia and respiratory insufficiency in the postoperative period. We have divided it into 3 main sections: 1) lung function changes induced by anesthesia and surgery, in which the impact on pulmonary mechanics, ventilation/perfusion changes and gas exchange are examined; 2) physiological implications of postoperative respiratory function secondary to decreased alveolar ventilation, development of atelectasis, and interstitial lung edema; and 3) clinical implications of postoperative respiratory failure. In this last section we analyze the current therapeutic modalities available to reduce the incidence of postoperative respiratory failure, as well as related morbidity and mortality.

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The Mechanics of the Respiratory System During Anesthesia

Cited by 76 publications

References 0 publications

Atropine Reversal of Hypercarbia during Enflurane Anaesthesia

Atropine Reversal of Hypercarbia during Enflurane Anaesthesia

A importância da pressão pleural na avaliação da mecânica respiratória

Lung function during anesthesia and respiratory insufficiency in the postoperative period: physiological and clinical implications

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