The measurement of metabolic gas exchange and minute volume by mass spectrometry alone

Davies, N.J.H.; Denison, D M

doi:10.1016/0034-5687(79)90029-x

Cited by 171 publications

(48 citation statements)

References 2 publications

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“…During exercise, patients breathed through a mouthpiece and a one-way valve attached to a mass spectrometer and a calibrated pneumotachographic system (AMIS 2000, Innovision) 20 for breath-by-breath gas analysis.…”

Section: Cardiopulmonary Exercise Testingmentioning

confidence: 99%

Nonsurgical Reduction of the Interventricular Septum in Patients with Hypertrophic Cardiomyopathy

et al. 2002

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Section: Cardiopulmonary Exercise Testingmentioning

confidence: 99%

Nonsurgical Reduction of the Interventricular Septum in Patients with Hypertrophic Cardiomyopathy

et al. 2002

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“…Respiratory gas exchanges (oxygen consumption and carbon dioxide production) were continuously measured using a mouthpiece and a mass spectrometer (MGA 2000, Airspec, Biggin Hill, UK). The volume of expired air was calculated using the argon dilution technique 12,13 : in brief, pure argon as tracer was added to the out¯ow through a mass¯ow controller (FC260, Tylan, Carson, USA) and then measured by the mass spectrometer. EE was calculated from measured oxygen consumption, with adjustments for carbon dioxide production, assuming that 15% oxydation was linked to protein.…”

Section: Measurement Of Energy Expenditurementioning

confidence: 99%

Postprandial thermogenesis and alimentary sensory stimulation in human subjects

1999

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OBJECTIVE: To study the role of alimentary sensory stimulation on the thermic effect of food. SUBJECTS: Nine male healthy volunteers (age: 20 ± 34 y, body mass index (BMI): 17.4 ± 25.3 kgam 2 ). DESIGN AND MEASUREMENTS: Four experimental situations were investigated on different days. Subjects: 1) ate a four course meal containing 2582 kJ (meal), 2) saw, smelt and tasted the same courses (alimentary sensory stimulation), 3) saw, smelt and tasted non-alimentary substances (non-alimentary sensory stimulation), 4) received directly into the stomach the previous meal (tube feeding). Energy expenditure (EE) was measured over a 20 min rest period, then for 110 min. RESULTS: The changes over midday rest EE were: meal 12.0%; alimentary sensory stimulation 3.2%; nonalimentary sensory stimulation 72.6%; tube feeding 5.7%. The increase in EE was higher after the meal than after either alimentary sensory stimulation (P`0.01) or tube feeding (P`0.01); the increases after the last two were, in turn, greater than after non-alimentary sensory stimulation (P`0.05). Only after alimentary sensory stimulation, was the increment in EE signi®cantly correlated with BMI (r 70.700; P`0.05). CONCLUSIONS: The early phase of postprandial thermogenesis therefore depends on both sensory and metabolic events. Furthermore, the sensory component was more pronounced in the lean subjects.

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“…Ventilatory measurements were made using helium dilution mixed expired gas analysis [10]. If an inert tracer gas (helium) is injected at a known constant rate into a stream of expired air then the flow of any component in that mixture may be calculated by measuring the concentrations downstream.…”

Section: Ventilatory Measurementsmentioning

confidence: 99%

Ventilatory variables in normal children during rest and exercise

Rosenthal¹,

Bush²

2000

Eur Respir J

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The aim of this study was to provide a complete description of normal ventilation at rest and exercise in children and to determine how best to correct for body size.One-hundred and six children aged 8±17 years (55 male) underwent incremental bicycle exercise testing from rest to exhaustion in 3 min, 15 W . m -2 steps and thence through 9 min recovery. All variables were calculated using helium dilution mixed expired gas analysis together with measures of alveolar gas concentrations from continuous measurement at the mouth, all via an AMIS 2000 quadrupole mass spectrometer.Surface area was the best single measure to correct for body size but always explained <37% of the variance. Thus for example, surface area corrected oxygen consumption at rest in males was greater than females. Data is presented at rest, each work load and at "maximum" exercise. When presented per watt of work at each work load, this permits comparison of adaptability to exercise between sexes and age groups. Exercise appears to terminate when respiration reaches 45 and 40 breaths . min -1 in males and females respectively and when alveolar oxygen concentrations rise.This simple protocol and near complete data set ought to permit accurate comparison with disease groups.

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The measurement of metabolic gas exchange and minute volume by mass spectrometry alone

Cited by 171 publications

References 2 publications

Nonsurgical Reduction of the Interventricular Septum in Patients with Hypertrophic Cardiomyopathy

Nonsurgical Reduction of the Interventricular Septum in Patients with Hypertrophic Cardiomyopathy

Postprandial thermogenesis and alimentary sensory stimulation in human subjects

Ventilatory variables in normal children during rest and exercise

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