Ta 2 O 5 waveguides offer great potential for high-density active photonic crystal circuits and their combination with rare-earth dopants for active devices is of interest for increasing their potential functionality. To this end, neodymium-doped Ta 2 O 5 rib waveguide lasers have been fabricated on an oxidized silicon wafer by RF sputtering and argon ion-beam milling and the first laser action in this material has been demonstrated. Lasing was observed at wavelengths between 1060nm and 1080nm and an absorbed pump power threshold of 87mW was obtained.