The Maximal Expiratory Flow-Volume Curve in Normal Subjects in India

Udwadia, F.E.; Sunavala, Jamshed D; Shetye, Vasant; Jain, Praveen

doi:10.1378/chest.89.6.852

Cited by 24 publications

(18 citation statements)

References 9 publications

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“…Restriction was classified using the GOLD criteria of FVC < 80% [31]. Predicted values for FVC or FEV 6 , FEV 1 and PEFR were calculated using Indian norms [32]. …”

Section: Methodsmentioning

confidence: 99%

Indoor air pollution and its association with poor lung function, microalbuminuria and variations in blood pressure among kitchen workers in India: a cross-sectional study

et al. 2017

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BackgroundThe present study is an attempt to explore the association between kitchen indoor air pollutants and physiological profiles in kitchen workers with microalbuminuria (MAU) in north India (Lucknow) and south India (Coimbatore).MethodsThe subjects comprised 145 control subjects, 233 kitchen workers from north India and 186 kitchen workers from south India. Information related to the personal and occupational history and health of the subjects at both locations were collected using a custom-made questionnaire. Worker lung function was measured using a spirometer. Blood pressure was monitored using a sphygmomanometer. Urinary MAU was measured using a urine analyzer. Indoor air monitoring in kitchens for particulate matter (PM), total volatile organic compounds (TVOC), carbon dioxide (CO2) and carbon monoxide (CO) was conducted using indoor air quality monitors. The size and shape of PM in indoor air was assessed using a scanning electron microscope (SEM). Fourier transform infrared (FTIR) spectroscopy was used to detect organic or inorganic compounds in the air samples.ResultsParticulate matter concentrations (PM2.5 and PM1) were significantly higher in both north and south Indian kitchens than in non-kitchen areas. The concentrations of TVOC, CO and CO2 were higher in the kitchens of north and south India than in the control locations (non-kitchen areas). Coarse, fine and ultrafine particles and several elements were also detected in kitchens in both locations by SEM and elemental analysis. The FTIR spectra of kitchen indoor air at both locations show the presence of organic chemicals. Significant declines in systolic blood pressure and lung function were observed in the kitchen workers with MAU at both locations compared to those of the control subjects. A higher prevalence of obstruction cases with MAU was observed among the workers in the southern region than in the controls (p < 0.01).ConclusionsKitchen workers in south India have lower lung capacities and a greater risk of obstructive and restrictive abnormalities than their north Indian counterparts. The study showed that occupational exposure to multiple kitchen indoor air pollutants (ultrafine particles, PM2.5, PM1, TVOC, CO, CO2) and FTIR-derived compounds can be associated with a decline in lung function (restrictive and obstructive patterns) in kitchen workers with microalbuminuria. Further studies in different geographical locations in India among kitchen workers on a wider scale are required to validate the present findings.

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“…Restriction was classified using the GOLD criteria of FVC < 80% [31]. Predicted values for FVC or FEV 6 , FEV 1 and PEFR were calculated using Indian norms [32]. …”

Section: Methodsmentioning

confidence: 99%

Indoor air pollution and its association with poor lung function, microalbuminuria and variations in blood pressure among kitchen workers in India: a cross-sectional study

et al. 2017

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“…Its importance in assessing small airway function has been reviewed and discussed (Hyatt and Black, 1973;Pride, 2001). However existing data on the MEFV loop in Indian populations at sea level is scanty (Udwadia et al, 1986;Patel et al, 1987, Kuppurao andVijayan, 1988).…”

Section: Apte and Raomentioning

confidence: 99%

The Maximum Expiratory Flow-Volume Loop in Natives of Ladakh and Acclimatized Lowlanders

Apte

Rao²

2005

High Altitude Medicine & Biology

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Differences in static and dynamic volumes may exist between high altitude residents of Indian Himalayas and their South American counterparts, as well as with acclimatized lowlander sojourners. Maximum expiratory flow-volume loops were recorded in healthy native highlanders of Ladakh (NH, N = 75) and in healthy acclimatized lowlanders (AL, N = 32) at an altitude of 3450 m in the western Indian Himalayas. The forced vital capacity (FVC) and forced expiratory volume in the first second (FEV1), both corrected for a height of 168 cm, were significantly higher in NH [FVC: 5.02 (0.51) vs. 3.89 (0.45) L, p < 0.0001; FEV1: 4.27 (0.47) vs. 3.44 (0.37) L, p < 0.0001]. The flow rates at larger lung volumes (PEFR, FEF25, and FEF50) were similar in the two groups. The NH showed significantly higher flow rates at low lung volumes, that is, FEF75 and FEF75-85% [FEF75: 2.03 (0.69) vs. 1.70 (0.52) L/s, p = 0.0092; FEF75-85%: 1.42 (0.54) vs. 1.06 (0.35) L/s, p = 0.0001]. The exact mechanisms allowing the higher flow rates at low lung volumes remain to be elucidated, but it is possible that these findings may indicate an inherited adaptive response in the Ladakhi highlander.

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“…But some have found significantly higher spirometric values in standing position than in sitting position [2]. Spirometric references values in general use today in India have been derived from data collected in sitting position [3,4]. Considering the chance of misdiagnosing patients in case of wrong interpretation of spirometry, it is imperative to know whether or not measurements taken in sitting position are significantly different than those taken in standing position and invite a false reading.…”

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Spirometric Values in Sitting, Standing and Supine Position

Patel¹,

Thakar²

2015

JLPRR

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IntroductionSpirometry is a physiological test that measures how an individual inhales or exhales volumes of air as a function of time. The primary signal measured in spirometry may be volume or flow. Spirometry is invaluable as a screening test of general respiratory health. It is commonly used to distinguish between restrictive and obstructive lung diseases, identifying patients susceptible to pulmonary barotraumas and bronchial hyper responsivity. It is also used in assessing pre-operative anesthetic risk in patients and patients about to undergo cardiothoracic surgery and to measure the efficacy of treatment of pulmonary diseases that show quantifiable defects [1].According to recent guideline of standardization of spirometry, both standing and sitting positions are acceptable [1]. But some have found significantly higher spirometric values in standing position than in sitting position [2]. Spirometric references values in general use today in India have been derived from data collected in sitting position [3,4]. Considering the chance of misdiagnosing patients in case of wrong interpretation of spirometry, it is imperative to know whether or not measurements taken in sitting position are significantly different than those taken in standing position and invite a false reading. The effect of sitting, standing and supine position on spirometric values has not been well studied in healthy subjects. Spirometric Values in Sitting, Standing and Supine PositionResearch Article Differences in the lung function of healthy subjects in the supine position compared with sitting position are of interest because these are the positions usually assumed during general anesthesia and more severe illness. Many times patient's lung functions need to be evaluate pre operatively but patients are not able to sit due to some reason, in which supine position must be used. Studies have shown that spirometric values decrease in supine position as compared to sitting position. But magnitude of change may be different [5,6]. So, it is also important to know the magnitude of difference occurs in lung functions in supine position. To, best of our knowledge none of the study has been published in Standard English literature from India.The aims of the study were to compare the spirometric values between sitting position and supine/standing position. This study was also aimed to find magnitude of change when going from sitting to supine position in order to help in interpreting the results of spirometry done in patients who are unable to sit upright and have to perform the test in supine positions. MethodsThe present study was carried out in SBKS Medical Institute & Research Centre, Piparia, Vadodara from March 2010 to April 2010. A prior approval from institutional ethical committee was taken. In this study 45 healthy non smoker subjects were chosen from volunteers among medical students and were asked Abstract Background: Spirometry may be done either in sitting or standing position. The effect of sitting, standing and supine position on ...

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The Maximal Expiratory Flow-Volume Curve in Normal Subjects in India

Cited by 24 publications

References 9 publications

Indoor air pollution and its association with poor lung function, microalbuminuria and variations in blood pressure among kitchen workers in India: a cross-sectional study

Indoor air pollution and its association with poor lung function, microalbuminuria and variations in blood pressure among kitchen workers in India: a cross-sectional study

The Maximum Expiratory Flow-Volume Loop in Natives of Ladakh and Acclimatized Lowlanders

Spirometric Values in Sitting, Standing and Supine Position

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