The masquerades of female pelvic tuberculosis: Case reports and review of literature on clinical presentations and diagnosis

Chow, T.W.; Lim, Boon Kiong; Sivanesaratnam, V.

doi:10.1046/j.1341-8076.2002.00041.x

Cited by 63 publications

(47 citation statements)

References 16 publications

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“…Morgagni first described genital tuberculosis in the mid eighteenth century and the tuberculous bacillus was discovered in 1882 by Koch (1). Tuberculosis is the second most common cause of death worldwide amongst communicable diseases.…”

Section: Introductionmentioning

confidence: 99%

Histopathologic analysis of female genital tuberculosis: a fifteen-year retrospective study of 110 cases in eastern india

Mondal¹

2013

TJPATH

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Objective: Tuberculosis remains a global health problem and is an important cause of morbidity and mortality. Female genital tuberculosis is rare in the western world, but relevant in developing countries like India. The aim of this study was to determine histologic findings of different parts of the female genital tract affected by tuberculosis and to correlate it with other features. Material and Method:A total number of 110 cases of female genital tuberculosis from 92 patients were included over a period of 15 years. The age range of the patients was 17 to 45 years with a mean of 26.3. The diagnostic procedures used were curettage biopsy, hysterectomy, histologic examination, culture, Mycobacterium Tuberculosispolymerase chain reaction, laparoscopy, hysterosalpingography and ultrasonography. Results:Patients with female genital tuberculosis presented with infertility (65-70%), pelvic/ abdominal pain (50-55%) and menstrual disturbances (20-25%). Female genital tuberculosis involved the vulva (2), vagina (1), cervix (5), endometrium (66), fallopian tube (24) and ovaries (12). Out of 66 endometrial tuberculosis cases, proliferative, secretory endometrium and atrophic endometrium were seen in 53, 9, and 4 cases, respectively. HIV co-infection was found only in 5 cases and acid-fast bacilli in tissue sections were detected in 7 cases. Conclusion:Female genital tuberculosis is not uncommon in developing countries and is an important cause of infertility. Though the fallopian tube was the most common site in many studies, the endometrium was the commonest site in this study. Sonuç: Kadın genital sistemi tüberkülozu gelişmekte olan ülkelerde nadir değildir ve infertilitenin önemli bir nedenidir. Çoğu çalışmada tubular en sık tutulan organ olmasına karşılık, çalışmamızda endometrium en sık tutulan organ olarak dikkati çekmektedir.

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Section: Introductionmentioning

confidence: 99%

Histopathologic analysis of female genital tuberculosis: a fifteen-year retrospective study of 110 cases in eastern india

Mondal¹

2013

TJPATH

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“…Although syncytiotrophoblastic giant cells have rarely been described in YST (1), other types of giant cells or granulomatous reaction have not been reported in YST to the best of our knowledge. in the case under study, we found a profound granulomatous reaction in the form of The differential diagnosis of a granulomatous reaction in the ovary includes infections, especially tuberculosis, and non-infective lesions such as sarcoidosis, Crohn's disease, xanthogranulomatous oophritis, foreign body and post-operative granulomas (2)(3)(4)(5)(6)(7)(8). Tuberculosis is an important cause of infertility and tubo-ovarian mass in india.…”

Section: Discussionmentioning

confidence: 80%

Ovarian yolk sac tumor with granulomatous reaction resembling tuberculosis – a unique presentation

Vasenwala

Sabzposh²,

Ansari³

et al. 2013

TJPATH

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Yolk sac tumors (endodermal sinus tumors) are an important subgroup of germ cell tumors of the ovary. They are seen in young females and are highly aggressive, but respond well to treatment. Although different morphological patterns can be seen on light microscopy, granulomatous reaction and giant cells are a very rare occurrence. We report the case of a young female with ovarian yolk-sac tumor in which a widespread granulomatous reaction was seen, causing a diagnostic dilemma.

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“…8,9 The fallopian tubes are affected in almost 100% of the cases followed by the endometrium in 50%, ovaries in 20%, cervix in 5%, and vagina and vulva in <1%. 10,11 Patients with genital tuberculosis are usually young women diagnosed during infertility work up. Genital tuberculosis is rare in postmenopausal women and responsible for only approximately 1% of postmenopausal bleeding, if symptomatic.…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic postmenopausal endometrial tuberculosis:a rare case report

Priyadharshini¹,

Shantha²

2017

Int J Reprod Contracept Obstet Gynecol

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Tuberculosis remains a global health problem, primarily in developing countries. Genital tuberculosis is common in young women mostly detected during infertility work up. Mycobacterial infection in postmenopausal women is an extremely rare disease. After menopause, tuberculosis of the endometrium is a rare possibility probably because of thedecreased vascularity of the tissues. We present here a case of asymptomatic postmenopausal woman who was suspected as endometrial carcinoma initially by abnormal endometrial pattern in ultrasound done as a part of regular health check-up. In endometrial biopsy we found pus draining. Diagnosed as endometrial tuberculosis by pathologic examination and polymerase chain reaction. She was put on anti-tuberculosis treatment. After completion of treatment, she was doing well. Thus, we conclude saying endometrial tuberculosis should also be suspected in postmenopausal women with abnormal endometrial pattern.

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The masquerades of female pelvic tuberculosis: Case reports and review of literature on clinical presentations and diagnosis

Cited by 63 publications

References 16 publications

Histopathologic analysis of female genital tuberculosis: a fifteen-year retrospective study of 110 cases in eastern india

Histopathologic analysis of female genital tuberculosis: a fifteen-year retrospective study of 110 cases in eastern india

Ovarian yolk sac tumor with granulomatous reaction resembling tuberculosis – a unique presentation

Asymptomatic postmenopausal endometrial tuberculosis:a rare case report

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