The MAP Client: User-Friendly Musculoskeletal Modelling Workflows

Zhang, Ju; Sorby, Hugh; Clement, John G.; Thomas, C. David L.; Hunter, Peter; Nielsen, Poul M. F.; Lloyd, David G.; Taylor, Mark; Besier, Thor F.

doi:10.1007/978-3-319-12057-7_21

Cited by 58 publications

(45 citation statements)

References 12 publications

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“…The Musculoskeletal Atlas Project Client 20 containing shape models of the pelvis and lower limbs was used to scale a generic musculoskeletal model (Gait2392) 21 . This approach has been shown to better reflect individual bony geometry compared to traditional linear scaling 15 .…”

Section: Methodsmentioning

confidence: 99%

Lower functioning patients demonstrate atypical hip joint loading before and following total hip arthroplasty for osteoarthritis

Bahl

Arnold

Taylor

et al. 2020

Journal Orthopaedic Research

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Previous studies have established that up to 1 year post total hip arthroplasty (THA), patients do not recover normal function and the magnitude of hip joint loading remains reduced compared to healthy individuals. However, the temporal nature of the loading profile has not been considered to identify individuals who are at a greater risk of poor functional outcomes following THA. This study aimed to determine changes to the profile and magnitude of the resultant hip joint reaction force before and up to 6 months post‐primary THA, and factors associated with atypical loading profiles. Hip joint loading was computed using a personalized lower‐limb musculoskeletal model in 43 participants awaiting primary THA for osteoarthritis (mean age: SD = 65, 14 years; body mass index: SD = 30, 5 kg/m2) before and up to 6 months after THA. Atypical, single‐peak loading profiles were observed for 11 patients before surgery, where four showed a single peak at 6 months. Patients displaying a single‐peak profile walked slower (mean difference: −0.4 m/s) compared to individuals displaying double‐peak profile (P = <.001) and had significantly reduced sagittal plane hip range of motion during gait (mean difference −9.6°, P = <.001). Self‐reported pain, function, and stiffness did not differentiate between patients with a single or double‐peak loading profile. Individuals with a single‐peak force profile did not meet the minimal clinically important hip range of motion during gait and would be classified as low‐functioning THA patients. Clinical Relevance: The temporal nature of the force profile may help to identify individuals who are at the greatest risk of poor functional outcomes after THA.

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Section: Methodsmentioning

confidence: 99%

Lower functioning patients demonstrate atypical hip joint loading before and following total hip arthroplasty for osteoarthritis

Bahl

Arnold

Taylor

et al. 2020

Journal Orthopaedic Research

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“…The body anatomy in the model can be informed by medical imaging [66][67][68] or extracted from population databases [69,70]. Statistical methods have been developed for improving the anatomical fidelity in the model using the limited set of information typically available in a clinical environment [71,72]. Real-time or near real-time numerical methods have been developed to predict muscle and joint force [73], bone strains [74,75] and strength [76].…”

Section: A Perspective Toward Personalized Exercise Prescriptionmentioning

confidence: 99%

Modelling Human Locomotion to Inform Exercise Prescription for Osteoporosis

Martelli

Beck

Saxby

et al. 2020

Curr Osteoporos Rep

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Purpose of Review We review the literature on hip fracture mechanics and models of hip strain during exercise to postulate the exercise regimen for best promoting hip strength. Recent Findings The superior neck is a common location for hip fracture and a relevant exercise target for osteoporosis. Current modelling studies showed that fast walking and stair ambulation, but not necessarily running, optimally load the femoral neck and therefore theoretically would mitigate the natural age-related bone decline, being easily integrated into routine daily activity. High intensity jumps and hopping have been shown to promote anabolic response by inducing high strain in the superior anterior neck. Multidirectional exercises may cause beneficial non-habitual strain patterns across the entire femoral neck. Resistance knee flexion and hip extension exercises can induce high strain in the superior neck when performed using maximal resistance loadings in the average population. Summary Exercise can stimulate an anabolic response of the femoral neck either by causing higher than normal bone strain over the entire hip region or by causing bending of the neck and localized strain in the superior cortex. Digital technologies have enabled studying interdependences between anatomy, bone distribution, exercise, strain and metabolism and may soon enable personalized prescription of exercise for optimal hip strength.

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“…We have demonstrated shape model‐based workflows for generating 3D morphology from sparse data . These workflows combine data routinely collected in gait laboratories (motion capture marker coordinates, anthropometric measurements) and partial segmented surfaces (e.g., from the hip or knee) to generate 3D surface meshes of the pelvis, femur, patella, tibia, and fibula.…”

Section: From Rigid‐body To Continuum Models Using Statistical Modelsmentioning

confidence: 99%

“…These workflows have been implemented in the open‐source Musculoskeletal Atlas Project (MAP) Client software and are freely available to the community . The MAP (Figure ) aims to consolidate into one common platform the many steps involved in musculoskeletal model generation (e.g., segmentation, registration, and mesh fitting) as well as the statistical models on which they depend.…”

Section: From Rigid‐body To Continuum Models Using Statistical Modelsmentioning

confidence: 99%

Toward modeling locomotion using electromyography‐informed 3D models: application to cerebral palsy

Sartori

Fernandez

Modenese

et al. 2016

WIREs Mechanisms of Disease

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The MAP Client: User-Friendly Musculoskeletal Modelling Workflows

Cited by 58 publications

References 12 publications

Lower functioning patients demonstrate atypical hip joint loading before and following total hip arthroplasty for osteoarthritis

Lower functioning patients demonstrate atypical hip joint loading before and following total hip arthroplasty for osteoarthritis

Modelling Human Locomotion to Inform Exercise Prescription for Osteoporosis

Toward modeling locomotion using electromyography‐informed 3D models: application to cerebral palsy

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