The manufacture of a thin‐film LCD

Bobrov, Y.; Fennell, L.; Lazarev, Pavel; Paukshto, Michael; Remizov, S. V.

doi:10.1889/1.1827884

Cited by 16 publications

(14 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…BioBridge resorbable collagen scaffolds (Fibralign Corporation, Union City, CA, USA) were produced according to a process based on the technology developed for liquid crystal display manufacturing [14, 15] that is suitable for lyotropic liquid crystal materials, as described previously [2, 3]. In brief, purified monomeric bovine type I collagen solution in a liquid crystal state [16, 17] was sheared onto a plastic substrate [18] to produce one micron thin membrane formed of about 30 nm diameter parallel-aligned fibrils.…”

Section: Methodsmentioning

confidence: 99%

Aligned nanofibrillar collagen scaffolds – Guiding lymphangiogenesis for treatment of acquired lymphedema

et al. 2016

View full text Add to dashboard Cite

Secondary lymphedema is a common disorder associated with acquired functional impairment of the lymphatic system. The goal of this study was to evaluate the therapeutic efficacy of aligned nanofibrillar collagen scaffolds (BioBridge) positioned across the area of lymphatic obstruction in guiding lymphatic regeneration. In a porcine model of acquired lymphedema, animals were treated with BioBridge scaffolds, alone or in conjunction with autologous lymph node transfer as a source of endogenous lymphatic growth factor. They were compared with a surgical control group and a second control group in which the implanted BioBridge was supplemented with exogenous vascular endothelial growth factor-C (VEGF-C). Three months after implantation, immunofluorescence staining of lymphatic vessels demonstrated a significant increase in lymphatic collectors within close proximity to the scaffolds. To quantify the functional impact of scaffold implantation, bioimpedance was used as an early indicator of extracellular fluid accumulation. In comparison to the levels prior to implantation, the bioimpedance ratio was significantly improved only in the experimental BioBridge recipients with or without lymph node transfer, suggesting restoration of functional lymphatic drainage. These results further correlated with quantifiable lymphatic collectors, as visualized by contrast-enhanced computed tomography. They demonstrate the therapeutic potential of BioBridge scaffolds in secondary lymphedema.

show abstract

Section: Methodsmentioning

confidence: 99%

Aligned nanofibrillar collagen scaffolds – Guiding lymphangiogenesis for treatment of acquired lymphedema

et al. 2016

View full text Add to dashboard Cite

show abstract

“…14 In brief, purified monomeric bovine type I collagen solution (Advanced Biomatrix) was concentrated to reach a liquid crystal state 25, 29, 44, 45 and then sheared onto glass or plastic surface, 46 creating thin membranes with parallel-aligned braided nanofibrillar orientation with 30 nm fibril diameter (Fig. 1).…”

Section: Methodsmentioning

confidence: 99%

Aligned-Braided Nanofibrillar Scaffold with Endothelial Cells Enhances Arteriogenesis

et al. 2015

View full text Add to dashboard Cite

The objective of this study was to enhance the angiogenic capacity of endothelial cells (ECs) using nano-scale signaling cues from aligned nanofibrillar scaffolds in the setting of tissue ischemia. Thread-like nanofibrillar scaffolds with porous structure were fabricated from aligned-braided membranes generated under shear from liquid crystal collagen solution. Human ECs showed greater outgrowth from aligned scaffolds than from non-patterned scaffolds. Integrin α1 was in part responsible for the enhanced cellular outgrowth on aligned nanofibrillar scaffolds, as the effect was abrogated by integrin α1 inhibition. To test the efficacy of EC-seeded aligned nanofibrillar scaffolds in improving neovascularization in vivo, the ischemic limbs of mice were treated with: EC-seeded aligned nanofibrillar scaffold; EC-seeded non-patterned scaffold; ECs in saline; aligned nanofibrillar scaffold alone; or no treatment. After 14 days, laser Doppler blood spectroscopy demonstrated significant improvement in blood perfusion recovery when treated with EC-seeded aligned nanofibrillar scaffolds, in comparison to ECs in saline or no treatment. In ischemic hindlimbs treated with scaffolds seeded with human ECs derived from induced pluripotent stem cells (iPSC-ECs), single-walled carbon nanotube (SWNT) fluorophores were systemically delivered to quantify microvascular density after 28 days. Near infrared-II (NIR-II, 1000–1700 nm) imaging of SWNT fluorophores demonstrated that iPSC-EC-seeded aligned scaffolds group showed significantly higher microvascular density than the saline or cells groups. These data suggest that treatment with EC-seeded aligned nanofibrillar scaffolds improved blood perfusion and arteriogenesis, when compared to treatment with cells alone or scaffold alone, and have important implications in the design of therapeutic cell delivery strategies

show abstract

“…[6][7][8] At certain concentration, supramolecules are converted into a liquidcrystalline state to form a lyotropic liquid crystal, which is the second step of ordering. The lyotropic liquid crystal is deposited under the action of a shear force (or meniscus force) onto a substrate based on a Mayer Rod or Slot-die coating technique, [2][3][4][5][6][9][10][11] so that the shear force (or the meniscus) direction determines the crystal axis direction in the resulting solid crystal film. This shear-force-assisted directional deposition is the third step of ordering, representing the global ordering of the crystalline or polycrystalline structure on the substrate surface.…”

Section: Cascade Crystallization Processmentioning

confidence: 99%

“…The Cascade Crystallization process is used for production of thin crystalline films (TCF) of Optiva's materials. [1][2][3][4][9][10][11][12][13][14] TCFs formed by dye molecules exhibit strong anisotropy of refraction and absorption 15,16 which makes them unique nano-scale polarizing films. [1][2][3][4][12][13][14][15][16] TCF exhibits properties of an E-type polarizer.…”

Section: Cascade Crystallization Processmentioning

confidence: 99%

Translucent LCDs

Gusel'nikov¹,

Lazarev²,

Paukshto³

et al. 2005

J Soc Info Display

Self Cite

View full text Add to dashboard Cite

Abstract— Current LCD designs have about 5–7% transmittance in the white state without the use of DBEF3M (double brightness enhancing film) and up to 10–14% with DBEF film. We presented a design which can further increase the brightness by up to 60%. The basics for this design are new Optiva materials which have a high birefringence about 0.3–0.4 and low absorption losses in the visible spectrum. This material can be used to produce multilayer interference reflective polarizer and polarization interference color filters. Initial prototypes of these interference elements will be discussed in the paper.

show abstract

The manufacture of a thin‐film LCD

Abstract: LCDs with internal polarizers were designed and fabricated as production prototype TN-LCDs. Optiva™ Thin Crystalline Films (TCFs) were used as the polarizers for these displays. The design and processes for fabrication of a TN-LCD with Optiva internal polarizers will be discussed.

Cited by 16 publications

References 2 publications

Aligned nanofibrillar collagen scaffolds – Guiding lymphangiogenesis for treatment of acquired lymphedema

Aligned nanofibrillar collagen scaffolds – Guiding lymphangiogenesis for treatment of acquired lymphedema

Aligned-Braided Nanofibrillar Scaffold with Endothelial Cells Enhances Arteriogenesis

Translucent LCDs

Contact Info

Product

Resources

About