“…At the same time, we should note that in the case of other amines, or using KOH instead of NaOH, the direction of the reaction was different, giving 9-thia-3,7-diazabicyclo[3.3.1]nonanes 117 as the final products (Scheme 45). 146,147 An unusual method for the construction of imidazo[1,5-c]-[1,3,5]thiadiazine system has been described. 148 (2), [109][110][111][112][113][114][115][116][117][118][119][120][121][122][123][124][125][126][127] Various S,N-binucleophilic compounds reacted with perfluoromethyleneimine 123; 151 the reaction can be considered as a special case of aminoalkylation.…”