2012
DOI: 10.1007/s11172-012-0298-9
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The Mannich-type interaction of sulfur-containing CH acids with formaldehyde and primary amines

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Cited by 2 publications
(2 citation statements)
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“…According to literature data, 146 the aminomethylation of activated sulfone 115 with methylamine and CH 2 O in the presence of 20% KOH gave a quantitative yield of thiadiazine 1,1-dioxide 116. At the same time, we should note that in the case of other amines, or using KOH instead of NaOH, the direction of the reaction was different, giving 9-thia-3,7-diazabicyclo[3.3.1]nonanes 117 as the final products (Scheme 45).…”
Section: Other Methods For the Preparation Of 135-thiadiazine Derivmentioning
confidence: 89%
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“…According to literature data, 146 the aminomethylation of activated sulfone 115 with methylamine and CH 2 O in the presence of 20% KOH gave a quantitative yield of thiadiazine 1,1-dioxide 116. At the same time, we should note that in the case of other amines, or using KOH instead of NaOH, the direction of the reaction was different, giving 9-thia-3,7-diazabicyclo[3.3.1]nonanes 117 as the final products (Scheme 45).…”
Section: Other Methods For the Preparation Of 135-thiadiazine Derivmentioning
confidence: 89%
“…At the same time, we should note that in the case of other amines, or using KOH instead of NaOH, the direction of the reaction was different, giving 9-thia-3,7-diazabicyclo[3.3.1]nonanes 117 as the final products (Scheme 45). 146,147 An unusual method for the construction of imidazo[1,5-c]-[1,3,5]thiadiazine system has been described. 148 (2), [109][110][111][112][113][114][115][116][117][118][119][120][121][122][123][124][125][126][127] Various S,N-binucleophilic compounds reacted with perfluoromethyleneimine 123; 151 the reaction can be considered as a special case of aminoalkylation.…”
Section: Other Methods For the Preparation Of 135-thiadiazine Derivmentioning
confidence: 99%