Abstract:Most peripheral arterial aneurysms are pseudoaneurysms and are iatrogenic or related to trauma. They can be treated by several techniques that can be performed by the radiologist, negating the need for surgery. Ultrasound guided compression repair is usually the treatment of choice, but is not always successful. The number of available treatment options reflects the varying site and nature of pseudoaneurysms and perhaps the lack of a consistently reliable method. We have successfully treated 13 patients with p… Show more
“…Since that time, ultrasound-guided compression (USGC) repair, ultrasound-guided thrombin injection (UGTI), and a whole host of other treatment modalities such as FemStop compression devices, 21 coil insertion, 22 fibrin adhesives, 23 or balloon occlusion have been used with variable success. The 3 most common treatment strategies are discussed below in more detail.…”
“…Since that time, ultrasound-guided compression (USGC) repair, ultrasound-guided thrombin injection (UGTI), and a whole host of other treatment modalities such as FemStop compression devices, 21 coil insertion, 22 fibrin adhesives, 23 or balloon occlusion have been used with variable success. The 3 most common treatment strategies are discussed below in more detail.…”
“…Loose and Haslam [45] described the technique of balloon tamponade of femoral artery with a percutaneous transluminal angioplasty (PTA) balloon to prevent distal embolization during pseudoaneurysm sac injection with fibrin adhesive (Beriplast P, Centeon, Marburg, Germany). The aneurysm neck is localized using angiography, and an angioplasty balloon is used to occlude the pseudoaneurysm.…”
Percutaneous cardiac catheterization and endovascular procedures are associated with complications at the vascular access site. While surgery has been the traditional treatment for vascular access complications, the current state of the art permits percutaneous management of many access site complications. Surgical repair may be required only when percutaneous methods fail, are not available, or are unsuitable.
“…They used an endoluminal balloon to protect the femoral artery and injected the fibrinogen substrate first, followed by the thrombin immediately afterwards. Loose and Haslam 23 observed thrombosis in all 13 cases treated this way.…”
Introduction: Femoral pseudoaneurysms are a complication that occurs in connection with up to 8% of percutaneous procedures. Of the available treatments, ultrasound guided thrombin injection has a high success rate and is welltolerated by patients. The combination of thrombin and fibrinogen known as fibrin sealant forms a stable clot and can be used to treat pseudoaneurysms, particularly those with complex anatomy and larger size. Objective: To compare the results of treating femoral pseudoaneurysm in two ways: Group T was treated with thrombin alone and Group T+F was treated with fibrin sealant (thrombin+fibrinogen). Methods: A retrospective analysis was conducted of femoral pseudoaneurysm cases treated between January 2005 and December 2012. Results: Twenty-eight patients were treated, 21 with thrombin alone and seven with fibrin sealant. All patients in group T were treated successfully, but only four patients in group T+F were treated successfully (57.1% success rate in Group T+F, p<0.01). The three cases of failure in group T+F needed surgery and in one of these cases the complication was embolization to the femoral bifurcation. The pseudoaneurysms that were treated with fibrin sealant were larger (25 cm 3 in Group T and 57.7 cm 3 in Group T+F, p=0.02) and required larger volumes of thrombin (0.5 mL in Group T and 1.0 mL in Group T+F, p<0.01). There was one complication in Group T and two complications in Group T+F (p<0.01). Conclusions: Irrespective of the small number of cases reviewed, treatment with thrombin alone was superior to treating with fibrin sealant, since it caused few complications and was more effective at correcting pseudoaneurysms.
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