“…Plants have evolved complex, efficient mechanisms to cope with unfavorable environment. The response of transcriptional regulation, post-transcriptional modification, epigenetic regulation, and secondary metabolism to abiotic stress has been studied in previous studies in S. miltiorrhiza ( Marino et al, 2013 ; Dou et al, 2021 ; Karre et al, 2021 ; Tong et al, 2021 ; Wang et al, 2021 ). But, ubiquitination modification and degradation of functional proteins regulating the synthesis of medicinal active substance in S. miltiorrhiza is still unclear.…”