The Maintenance of Stability in the Newly Born: Part 2. Thermal Balance

McCance, R. A.

doi:10.1136/adc.34.178.459

Cited by 31 publications

(6 citation statements)

References 45 publications

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“…A ccording to th is (see ta b le 5), th e physiologic p o stn a ta l rise of C 0 2 o f th e re sp ira to ry a ir ran g es w ith in th e first m in u tes o f life betw een 26…”

Section: Resultsmentioning

confidence: 99%

Studies about Respiratory Regulation of the Newborn I. About the Respiratory Regulating Function of the Postnatal CO<sub>2</sub> Rise in the Alveolar Air of the Mature Born Infant after Uncomplicated Birth. (A Contribution to Examination of Newborn Babies with the Help of the Apgar Score)

Gleiss¹,

Holderberg²

1963

Neonatology

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“…A ccording to th is (see ta b le 5), th e physiologic p o stn a ta l rise of C 0 2 o f th e re sp ira to ry a ir ran g es w ith in th e first m in u tes o f life betw een 26…”

Section: Resultsmentioning

confidence: 99%

Studies about Respiratory Regulation of the Newborn I. About the Respiratory Regulating Function of the Postnatal CO<sub>2</sub> Rise in the Alveolar Air of the Mature Born Infant after Uncomplicated Birth. (A Contribution to Examination of Newborn Babies with the Help of the Apgar Score)

Gleiss¹,

Holderberg²

1963

Neonatology

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“…Illumination levels have also been shown to affect the activity and behaviour (including defecation rate) of different mouse strains in different ways (McClearn, 1960;Ross, Kessler, Nagy & Scott, 1966); defecation rate in rats can be increased under bright lighting (Williams, 1971). Light intensity has been shown to interact with chemical carcinogens in the mouse, the results differing among the tissues involved.…”

Section: ( I ) Intensitymentioning

confidence: 99%

Environmental Effects on Animals Used in Biomedical Research

Clough

1982

Biological Reviews

154

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Summary I. Reliability of the results of bio‐medical research clearly depends upon the animals used showing as standard responses as is possible. 2. The majority of animals used in this field are small, homoiothermic mammals which have sensitive and strong homeostatic mechanisms. If a change in ambient conditions is of sufficient magnitude to unbalance homeostasis, then the neuroendocrine system is stimulated so as to restore it, and this can interfere with the response to test conditions or agents. 3. The homeostatic effectors involved are diverse and can include both physiological and behavioural changes in the animal. These can affect metabolic rate, body temperature, activity, food consumption, hormone concentration, wake/sleep patterns, maturation, posture, lactation and many other bodily functions. Any of these changes is potentially capable of influencing experimental results. 4. The evidence presented shows how environmental factors may affect the outcome of experiments in the fields of animal behaviour, cancer research, immunology, pathology, pharmacology, psychology, reproduction, teratology and toxicology; particular attention is paid to the effects of ambient temperature, relative humidity, air movement and quality, light and sound. 5. While a constant, reproducible environment would be ideal, there is little possibility of controlling all the variables; nevertheless all investigators should minimize those environmental variables that have been shown to be important. 6. To enable other investigators to repeat experiments or carry out comparative studies, environmental conditions pertaining during an experiment should be adequately described in any publications.

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“…It is obvious that workers in these disciplines should live in practical harmony with one another. Increasing pressure is put on the clinician who must, as McCance (1959) observed, be able to understand the isolated functions on which the whole is based and be prepared to converse with the experts, seek the best information available and interpret the specialists' jargon.…”

Section: Defln Itionmentioning

confidence: 99%

Some Reflections on Clinical Research

Rossdale

1975

Equine Veterinary Journal

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SUMMARY The place of clinical research in the veterinary profession is discussed against the author's personal experiences and in the context of how research workers, clinicians, teachers and veterinary students might be brought into a more cohesive unit through the development of a Faculty of clinical research and experimental medicine. It is argued that students should receive training in research and teaching and that efforts should be made to break down the attitude of “them” and “us” which tends to separate the clinicians and academics. RÉSUMÉ La situation de la recherche clinique dans la profession vétérinaire est discutée par l'auteur, avec le souci de savoir comment les chercheurs, les praticiens, les enseignants et les étudiants pourraient coopérer plus efficacement. On pense ici que les étudiants devraient recevoir une formation d'enseignants et de chercheurs. Par ailleurs tous les efforts devraient être faits pour combler le fossé entre les vocations cliniques et “académiques”. ZUSAMMENFASSUNG Die Stellung der klinischen Forschung im tierärztlichen Beruf wird diskutiert aufgrund persönlicher Erfahrungen. Es wird auch besprochen wie Forscher, Kliniker, Lehrer und Studenten zu einer besser zusammenhängenden Einheit werden könnten durch die Entwicklung einer Fakultät für klinische Forschung und experimentelle Medizin. Es wird befürwortet, dass Studenten in Forschung und Lehre eingesetzt werden; es sei auch wünschenswert, die Unterteilung in “Sie” und “Uns” zu bekämpfen, weil sie zu einer Trennung von Akademikern und Klinikern führe.

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The Maintenance of Stability in the Newly Born: Part 2. Thermal Balance

Cited by 31 publications

References 45 publications

Studies about Respiratory Regulation of the Newborn I. About the Respiratory Regulating Function of the Postnatal CO<sub>2</sub> Rise in the Alveolar Air of the Mature Born Infant after Uncomplicated Birth. (A Contribution to Examination of Newborn Babies with the Help of the Apgar Score)

Studies about Respiratory Regulation of the Newborn I. About the Respiratory Regulating Function of the Postnatal CO<sub>2</sub> Rise in the Alveolar Air of the Mature Born Infant after Uncomplicated Birth. (A Contribution to Examination of Newborn Babies with the Help of the Apgar Score)

Environmental Effects on Animals Used in Biomedical Research

Some Reflections on Clinical Research

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