The Main Thing is to be Alive—Exploring Patients’ Experiences With Weight Gain After Liver Transplantation: A Qualitative Study

Beckmann, Sonja; Künzler-Heule, Patrizia; Kabut, Kajetan; Mauthner, Oliver

doi:10.3389/ti.2022.10256

Cited by 1 publication

(2 citation statements)

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“…Excessive weight gain and obesity are also frequent nutritional problems in the long term after LT. Studies report a mean weight gain between 2 and 9 kg within the first year post-LT [ 133 ]. In an article by Carias et al analyzing 207 patients, SO was detected in 13% of sarcopenic patients in pre-transplant and in 42% of patients six months after LT [ 134 ].…”

Section: Discussion and Future Considerationsmentioning

confidence: 99%

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Nutritional Strategies to Manage Malnutrition and Sarcopenia following Liver Transplantation: A Narrative Review

2023

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Persisting or newly developed malnutrition and sarcopenia after liver transplant (LT) are correlated with adverse health outcomes. This narrative review aims to examine the literature regarding nutrition strategies to manage malnutrition and sarcopenia after LT. The secondary aims are to provide an overview of the effect of nutrition strategies on the incidence of infections, hospital length of stay (LOS), acute cellular rejection (ACR), and mortality after LT. Four databases were searched. A total of 25 studies, mostly of mid–high quality, were included. Six studies found a beneficial effect on nutritional parameters using branched-chain amino acids (BCAA), immunomodulating diet (IMD), or enteral nutrition (EN) whereas two studies using beta-hydroxy-beta-methylbutyrate (HMB) found a beneficial effect on muscle mass and function. Fourteen studies using pre- or pro-biotics, IMD, and EN were effective in lowering infection and six studies using IMD, BCAA or HMB reported reduced hospital LOS. Finally, four studies using HMB and vitamin D were effective in reducing ACR and one study reported reduced mortality using vitamin D after LT. In conclusion, nutritional intervention after LT has different beneficial effects on malnutrition, sarcopenia, and other advert outcomes. Additional large and well-constructed RCTs using validated tools to assess nutritional status and sarcopenia are warranted to ensure more robust conclusions.

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Section: Discussion and Future Considerationsmentioning

confidence: 99%

“…At 2 and 3 years following transplantation, continuous weight gain contributes to new-onset obesity in 22–38% of patients [ 133 ]. Weight gain and obesity seem to be related to higher scores for specific eating behaviors of uncontrolled and emotional eating as well as cognitive restrain [ 138 ].…”

Section: Discussion and Future Considerationsmentioning

confidence: 99%