The magnitude of combined training-induced changes in executive functions is related to pre-training BDNF levels in middle-aged and older adults with Type 2 Diabetes Mellitus
Abstract:Background: Many cognitive functions are affected by Type 2 Diabetes Mellitus (T2DM). Aerobic plus resistance exercise training, known as combined training (CT), may mitigate or reverse the T2DM-related cognitive impairment by improving metabolic control. Brain-derived neurotrophic factor (BDNF) seems to modulate the cognitive functions of healthy and T2DM adults. However, the CT-effects on BDNF levels of T2DM subjects need to be better elucidated. Aim: To analyze the effects of 8-week CT on circulating BDNF l… Show more
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