“…Finally, since the present framework ascribes a central role to the LC-NE system, it follows that disturbances in the LC-NE system might affect creative cognition. For example, the LC-NE system has been implicated in highly overlapping sets of clinical disorders associated with either enhanced or impaired creativity (e.g., schizophrenia, bipolar disorder; Baas, Nijstad, Boot, & De Dreu, 2016;Kyaga et al, 2011;MacCabe, Sariasian, Almqvist, Lichtenstein, Larsson, & Kyaga, 2018;Simonton, 2014). Some evidence suggests that schizophrenic patients have increased locus NEUROECONOMICS AND CREATIVITY 29 coeruleus cell volumes (Marner, Søborg, & Pakkenberg, 2005), and type 1 (positive symptoms) schizophrenia has been associated with elevated norepinephrine and metabolites in the brain (Yamamoto & Hornykiewicz, 2004).…”