The long‐term outcomes of symptomatic congenital lobar emphysema patients

Abstract

Introduction Surgical (OP) management for symptomatic congenital lobar emphysema (CLE) is the standard of care with nonoperative (NOP) approach applied for asymptomatic cases. The aim of this study is to report the outcomes for NOP approach to the care of symptomatic CLE infants. Methods A retrospective study of CLE patients treated 2000−2021 at a single institution. Patients with CLE and respiratory symptoms were included. Results Overall, 23 children had symptomatic CLE, and 12 had NOP management. The median age at diagnosis was 38.5 days (50) in the NOP group versus 25 days (20) in the OP group (p = 0.31). There was no significant difference in the location of the involved lobe, term birth, postnatal diagnosis and gender, and both groups required noninvasive support in 33% of the cases. There was a trend towards higher frequency of oxygen support in the OP group preoperatively (89% vs. 42%, p = 0.07). The median length of stay was 14 days in the NOP group compared to a median postsurgery stay of 7.5 days in the OP group. In follow‐up, there was no significant difference in respiratory readmission in first year of life, growth delay, treatment with asthma medication or body mass index in the NOP versus OP group. None of the children in the NOP group required surgery during follow‐up. Conclusions A NOP approach for symptomatic CLE infants can have favorable long‐term outcomes. Further studies will be required to identify markers to aid in clinical decision‐making.

Intradiaphragmatic pulmonary sequestrations: a surgical challenge. Case series

“…An aberrant artery originating from the celiac trunk was identified supplying the mass within the diaphragm. Parents were instructed regarding the conservative approach for the emphysematous lesion ( 6 ) and the possibility to choose for removal or close follow up of the intradiaphragmatic mass. After surgical counselling, parents' preference was to remove the lesion, together with the emphysematous lobe.…”