The long-term effects of laser photocoagulation treatment in patients with diabetic retinopathy

A Prospective Study of Serum Lipids and Risk of Diabetic Macular Edema in Type 1 Diabetes

“…Moreover, in the ETDRS, the median cholesterol value when compared with the age-stratified distribution of the patients screened by the Lipids Research Clinics Program was at the 75th percentile, compared with approximately the 50th percentile in the DCCT (26). More specifically, ETDRS participants' total cholesterol ranged from 106 to 852 mg/dl, with the mean of 229 mg/dl (27), compared with total cholesterol ranging from 73 to 312 mg/dl, with a mean of 176 mg/dl in the DCCT. Additionally, in the ETDRS, 36% of participants had total cholesterol levels Ͼ240 mg/dl compared with Ͻ5% in DCCT subjects (28).…”

Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study

“…10 Since the ETDRS, focal and grid laser treatment have been the standard treatment for MO. A long-term follow-up study by Chew et al 11 found that a median of 16.7 years after the original study, 42% of patients had a visual acuity of 20/20 [logarithm of the minimum angle of resolution (log-MAR) 0] or better in their best eye, and 84% had a visual acuity of 20/40 (log-MAR 0.3) or better in their best eye. Nevertheless, laser treatment is not without risk and is not effective in all cases.…”

Antiangiogenic Therapy for Ischemic Retinopathies

“…This treatment approach has been proven effective in large randomized clinical trials at inducing long-term regression of neovascularization; however, such treatment can be associated with potentially vision threatening side-effects and a proportion of patients still continue to develop active neovascularization and consequent visual loss (Chew et al 2003).…”