The long‐term complications of posterior urethral valves

Posterior urethral valve

“…The bladder dysfunction that some of these patients have will be decisive in the development of their renal failure. [44,45] Poor compliance is associated with the worst prognosis [46] but other factors implicated in the worsened prognosis in the boys include age at diagnosis, renal dysplasia, renal function before and after valve ablation, VUR, UTI, proteinuria, hypertension, and initial treatment. [42,43] The level of serum creatinine at 1 year old is shown to have a greater predictive value than the level at the time of diagnosis.…”

Does Treatment With Clean Intermittent Catheterization in Boys With Posterior Urethral Valves Affect Bladder and Renal Function?

“…In these cases the treatment has been just as active as in the others and must be regarded as an investment in the future, ie to have controlled bladder function at the time of transplantation, which is of importance for survival of the graft. 9,12 Bladder treatment including CIC can also be suggested to influence bladder function based on our results. Poor compliance was seen in a third of the CIC group at the initial investigation and low compliance persisted in only 1 boy at age 4 years despite CIC.…”

The Genetic and Phenotypic Basis of Infertility in Men With Pediatric Urologic Disorders

“…[41, 42] Infertility in men with a history of PUV can be multifactorial. Retrograde ejaculation due to an open bladder neck is common.…”

“…[42] Patients with PUV and renal failure can also suffer from erectile dysfunction and reduced libido. [41] A higher rate of cryptorchidism among patients with PUV may also compromise fertility. Semen analyses in a series of 5 PUV patients demonstrated prolonged liquefaction time (40% of men), greater numbers of immotile sperm (all men), abnormally viscous semen (40%), and abnormal sperm agglutination (80%) suggesting that abnormalities in seminal plasma are also common in these patients.…”