The localization, origin, and impact of platelets in the tumor microenvironment are tumor type-dependent
Ophélie Le Chapelain,
Soumaya Jadoui,
Angèle Gros
et al.
Abstract:Background
How platelets interact with and influence the tumor microenvironment (TME) remains poorly characterized.
Methods
We compared the presence and participation of platelets in the TME of two tumors characterized by highly different TME, PyMT AT-3 mammary tumors and B16F1 melanoma.
Results
We show that whereas firmly adherent platelets continuously line tumor vessels of both AT-3 and B16F1 tumors… Show more
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