2011
DOI: 10.1007/s11882-011-0237-0
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The Likelihood of Remission of Food Allergy in Children: When Is the Optimal Time for Challenge?

Abstract: Although diagnostic testing methods for food hypersensitivity have improved over time, both in vivo and in vitro methods are significantly flawed, especially as evidenced by the frequent occurrence of false-positive test results. Because of these limitations, oral food challenge testing remains an essential element in the diagnosis and management of food allergy. In fact, the double-blind, placebo-controlled food challenge remains the gold standard for the diagnosis of food allergy. In this review, we focus on… Show more

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Cited by 6 publications
(2 citation statements)
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References 46 publications
(45 reference statements)
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“…In patients with persistent allergy with unchanged specific IgE levels for several years, testing can be performed less frequently over time 88 . Factors to consider before deciding to pursue an OFC include the chance of success, the potential for risk, and the preferences of the patient and family including the importance of the food to the diet 103 . Other important considerations may include patient age, history of reactions, family characteristics, and comorbidities (e.g.…”
Section: Natural Coursementioning
confidence: 99%
“…In patients with persistent allergy with unchanged specific IgE levels for several years, testing can be performed less frequently over time 88 . Factors to consider before deciding to pursue an OFC include the chance of success, the potential for risk, and the preferences of the patient and family including the importance of the food to the diet 103 . Other important considerations may include patient age, history of reactions, family characteristics, and comorbidities (e.g.…”
Section: Natural Coursementioning
confidence: 99%
“…First, they have been used to assess the accuracy of other diagnostic methods, including skin tests, patch tests, and measurement of allergen-specific IgE levels [8][9][10][11][12][13][14][15] . Second, they have been used to assess threshold doses for different allergenic foods, providing essential data for the establishment of guidelines for the food industry and revealing the potential risks of low-level allergen exposure [16][17][18] .…”
Section: Oral Challenge Testingmentioning
confidence: 99%