The level of dysbiosis of the oral cavity depends on the type of dental prosthesis of the patient

Abstract

The work was aimed to determine the level of oral dysbiosis of patients depending on the type of prosthetics constructures. MATERIALS AND METHODS: The study involved 48 patients with the presence in the oral cavity of fi xed dentures from 4 to 6 units with a service life of no more than 3 years. The samples of plaque from the vestibular surface of dentures were collected to determine the microorganisms in the gingival plaque. Bacteriological research was carried out by the multiplex polymerase chain reaction in real time using the Phemofl or 8 reagent kit. The degree of dysbiosis of the oral cavity was determined according to the classifi cation of V. Khazanova. RESULTS: The results of the study of patients' samples did not reveal signifi cant changes in the microbial landscape of the cervical areas. The total bacterial mass in the group of healthy individuals was lower than the total bacterial mass of patients in the investigated group signifi cantly. IV degree of oral dysbiosis with a decrease in the number of lactobacilli, streptococci was characteristic of patients of denture wearers. The II degree of dysbiosis in patients with metal-ceramic structures was established. Patients who used solid cast and metal-plastic structures were diagnosed with II-III degree of dysbiosis of the oral cavity. The worst indicators were characteristic of prosthesis wearers of stamped-brazed structures. CONCLUSIONS: Quantitative indicators of the composition of the microbiota of the cervical areas of denture wearers have signifi cant differences and different levels of dysbiosis of the oral cavity, depending on the type of dentures in the patients' mouth (Tab. 2, Fig. 1, Ref. 21).

Features of Changes in Indicators of Local Immunity of the Oral Cavity and Blood Serum of Patients Against the Background of Generalized Periodontitis and Type 2 Diabetes Mellitus

“…According to literature sources [4], diabetes mellitus is a significant risk factor for the development of inflammatory diseases of the oral cavity. Studies have demonstrated a bidirectional relationship between diabetes mellitus and periodontitis, with more severe periodontal tissue destruction in diabetic patients and poor glycemic control in patients with diabetes and periodontitis [5,6,7].…”

Application of Antimicrobial Nanoparticles of Metals and Their Oxides in Improving Dental Prostheses

“…Протимікробні НЧ є перспективною стратегією лікування і попередження інфекцій органів ротової порожнини [13] і можуть бути застосовані в різних галузях стоматології: терапевтичній, хірургічній, ортопедичній [14]. Оскільки відомо, що кількісні показники складу мікробіоти при зубному протезуванні мають значні відмінності та різний рівень дисбактеріозу порожнини рота залежно від типу протезів у роті пацієнтів [15] Втрата зубів достатньо поширена і часто лікується встановленням повних або часткових знімних зубних протезів. У ортопедичній стоматології зубні протези мають значний вплив на покращення якості догляду за порожниною рота [16].…”