2006
DOI: 10.1007/s00383-006-1793-6
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The leaking pancreatic duct in childhood chronic pancreatitis

Abstract: The leaking pancreatic duct in childhood chronic pancreatitis presents with ascites and pleural effusion and is a potentially lethal condition. Seven children with this condition were seen in the period 2003-2006. The correct diagnosis was not entertained till a raised serum amylase was discovered. The diagnosis was confirmed by very high levels of amylase in the aspirated abdominal or pleural fluid. Computerized tomogram was the most useful imaging study and demonstrated a dilated pancreatic duct. All childre… Show more

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Cited by 7 publications
(6 citation statements)
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References 13 publications
(18 reference statements)
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“…A pancreatic fistula resulting in a PPE or PA is confirmed with elevated amylase and protein content in the pleural and/or ascitic fluids, as described in both cases. Serum amylase may also be elevated [6,12]. Children with pancreatic fistulae usually present with significant malnutrition, low serum albumin <30 g/L, and a history of progressive abdominal distension [12].…”
Section: Discussionmentioning
confidence: 99%
“…A pancreatic fistula resulting in a PPE or PA is confirmed with elevated amylase and protein content in the pleural and/or ascitic fluids, as described in both cases. Serum amylase may also be elevated [6,12]. Children with pancreatic fistulae usually present with significant malnutrition, low serum albumin <30 g/L, and a history of progressive abdominal distension [12].…”
Section: Discussionmentioning
confidence: 99%
“…Two common mechanisms of pancreatic pleural effusion are transdiaphragmatic lymphatic blockage or pancreatico-pleural fistula secondary to leak and disruption of the pancreatic duct or pseudocyst. Left-sided pleural effusion, once considered a marker of acute pancreatitis, is indeed a poor prognostic indicator and is associated with 20% to 30% mortality [5][6][7][8].…”
Section: Acute Pancreatitis In Children Can Have Variable Presentatiomentioning
confidence: 99%
“…Blunt pancreatic injuries without ductal leak usually resolve with mere conservative management. On the other hand, damage to the ductal system, if inadequately treated or untreated, can result in prolonged morbidity [3,7].…”
Section: Vol 2 Issue 4 Oct -Dec 2016mentioning
confidence: 99%
“…3 Angiogram showing bleeding pseudo-aneurism in a replaced hepatic artery suspected by raised serum amylase and gross elevation of ascitic fluid amylase. Prompt and definitive surgical management is recommended for this potentially lethal condition [62]. Endoscopic therapy offers an excellent therapeutic alternative in patients with pancreatic ascites and pleural effusion [59,63].…”
Section: Pancreatic Ascitesmentioning
confidence: 99%