The Lausanne cohort Lc65+: a population-based prospective study of the manifestations, determinants and outcomes of frailty

Santos-Eggimann, Brigitte; Karmaniola, Athanassia; Seematter‐Bagnoud, Laurence; Spagnoli, Jacques; Büla, Christophe; Cornuz, Jacques; Rodondi, Nicolas; Vollenweider, Péter; Waeber, Gérard; Pécoud, A

doi:10.1186/1471-2318-8-20

Cited by 91 publications

(110 citation statements)

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“…This cross-sectional study used data from the population-based Lausanne cohort 65+ study (Lc65+)21 and two additional, stratified, random samples selected from population lists in the cantons of Vaud and Geneva 22. The pooled data set comprising 5300 community-dwelling adults aged 68 years and older is representative of older people in two French-speaking Swiss regions.…”

Section: Methodsmentioning

confidence: 99%

Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland

et al. 2017

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ObjectivesThe burden of multiple diagnoses is well documented in older people, but less is known about chronic symptoms, many of which are even not brought to medical attention. This study aimed to determine the prevalence of chronic symptoms, their relationships with disability in basic activities of daily living (BADL) and quality of life (QoL), and their public health impact.DesignA large cross-sectional population-based study.SettingCommunity in 2 regions of French-speaking Switzerland.ParticipantsCommunity-dwelling older adults aged 68 years and older in 2011 (N=5300).OutcomesDisability in BADL defined as difficulty or help needed with any of dressing, bathing, eating, getting in/out of bed or an arm chair, and using the toilet. Overall QoL dichotomised as favourable (ie, excellent or very good) or unfavourable (ie, good, fair or poor). Disturbance by any of the following 14 chronic symptoms for at least 6 months: joint pain, back pain, chest pain, dyspnoea, persistent cough, swollen legs, memory gaps, difficulty concentrating, difficulty making decisions, dizziness/vertigo, skin problems, stomach/intestine problems, urinary incontinence and impaired sexual life.ResultsOnly 17.1% of participants did not report being disturbed by any of these chronic symptoms. Weighted prevalence ranged from 3.1% (chest pain) to 47.7% (joint pain). Most chronic symptoms were significantly associated with disability in BADL or unfavourable QoL, with substantial gender differences. The number of chronic symptoms was significantly associated with disability in BADL and unfavourable QoL, with gradients suggesting dose–response relationships. Joint pain and back pain had the highest population attributable fractions.ConclusionsChronic symptoms are highly prevalent in older people, and are associated with disability in BADL and unfavourable QoL, particularly when multiple chronic symptoms co-occur. Owing to their high public health impact, musculoskeletal chronic symptoms represent good targets for preventive interventions.

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Section: Methodsmentioning

confidence: 99%

Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland

et al. 2017

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“…Details of Lc65+ have been reported (Santos-Eggimann, Karmaniola, et al, 2008). In brief, the original cohort consisted of 1422 subjects aged 65-70 at the time of study entry in 2004 who were randomly selected from the community and participated in a baseline assessment.…”

Section: Subjectsmentioning

confidence: 99%

Handwriting and pre-frailty in the Lausanne cohort 65+ (Lc65+) study

Camicioli

Mizrahi

Spagnoli

et al. 2015

Archives of Gerontology and Geriatrics

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“…To this end, we measured spatiotemporal as well as clearance gait parameters in a cohort of able-bodied adults over the age of 65 [14]. The assessment of these parameters was achieved using shoe-worn inertial sensors and corresponding previously validated algorithms [11,15,16,17].…”

Section: Introductionmentioning

confidence: 99%

Gait analysis using shoe-worn inertial sensors

Aminian

Dadashi

Mariani

et al. 2014

Proceedings of the 2014 ACM International Joint Conference on Pervasive and Ubiquitous Computing

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Spatiotemporal gait analysis with body worn inertial sensors improves diagnosis in clinical practice. Most of the gait performance measures are affected by walking speed. However, it has not been investigated that how much information foot clearance parameters share with the key parameters of gait performance domains. Using shoe-worn inertial sensors and previously validated algorithm we measured spatiotemporal as well as clearance gait parameters in a cohort of able-bodied adults over the age of 65 (N=879). Principal components analysis showed that variability of foot clearance parameters contribute to the main variability in gait data. Moreover, only weak to moderate correlation of gait speed and stride length with some clearance parameters has been observed. We recommend the assessment of clearance parameters during gait analysis in addition to parameters such as gait speed, bearing in mind the importance of foot clearance measures in obstacle negotiation, slipping and tripping related falls.

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The Lausanne cohort Lc65+: a population-based prospective study of the manifestations, determinants and outcomes of frailty

Cited by 91 publications

References 69 publications

Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland

Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland

Handwriting and pre-frailty in the Lausanne cohort 65+ (Lc65+) study

Gait analysis using shoe-worn inertial sensors

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