The Latin American School of Human and Medical Genetics: promoting education and collaboration in genetics and ethics applied to health sciences across the continent

Abstract

The Latin American Network of Human Genetics (RELAGH) created the Latin American School of Human and Medical Genetics (ELAG) to prepare young researchers and professionals of Latin America to deal with the growing challenge of the genomic medicine. ELAG promotes an annually course since 2005, which received 838 students from 17 Latin American countries over these 10 years. ELAG plays an important role to provide education in genetics applied to health sciences to fellows who live in countries with a less favorable economic situation. Influenced, among others, by the humanitarian perspective of José Maria Cantú, one of its founders, ELAG has always favored the discussion of ethical and social issues related to genetics in Latin America. Few initiatives in Latin America lasted 10 consecutive years. One of the factors responsible for the ELAG's success has been its group of faculty members, who contribute to a friendly environment prone to facilitating the exchange of their own experiences with young researchers.

Oral and craniofacial manifestations in a Hunter syndrome patient with hematopoietic stem cell transplantation: A case report

“…The following oral characteristics have also been reported for MPS II patients: diastema, open‐bite, posterior cross‐bite, narrow and deep palate, wide and flat palate, malocclusion, retention/delayed teeth, ectopic teeth, and thick lips . Our patient showed some of those features: thick lips, macroglossia, class I malocclusion with incisor crowding, right posterior cross‐bite, retained primary teeth, ectopic eruption, and enamel hypoplasia only on the erupted permanent teeth.…”

“…Cognitive and behavioral problems made it difficult to obtain clinical case documentation and to provide clinical dental care. In the literature, behavior disorders such anxiety, hyperactivity, aggression, and sleep upset have been reported . Neurological degeneration was found in 23.3% of 77 South American MPS II patients, while Chiong et al.…”

“…In the literature, behavior disorders such anxiety, hyperactivity, aggression, and sleep upset have been reported. 1,3 Neurological degeneration was found in 23.3% of 77 South American MPS II patients, 14 while Chiong et al 15 found that 91.3% of Filipino MPS II patients revealed development delay/mental disorders.…”

“…The spectrum of the disease ranges from mild chronic to severe forms . The clinical features of MPS II vary significantly from patient to patient, with differences in the age of onset of symptoms, disease rate progression, and severity of signs and symptoms …”