The Latex Story

Raulf, Monika

doi:10.1159/000358863

Cited by 32 publications

(40 citation statements)

References 50 publications

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“…A similar decline has been reported for HCWs . It is well known that HCWs are at higher risk of acquiring NRL allergy than the general population . Because of differences in study populations, test methods, and interventions, it is not possible to directly compare our data with results from studies focusing on HCWs.…”

Section: Discussionsupporting

confidence: 72%

“…It is well known that NRL, birch pollen, plants and some foods show cross‐reactivity . Our study showed that 64% of the NRL‐sensitized patients had a concomitant positive prick test reaction to birch pollen (Table ).…”

Section: Discussionmentioning

confidence: 56%

“…Today, nearly all industrial natural rubber latex (NRL) products are obtained from the rubber tree, Hevea brasiliensis that produces a milky sap that, after several manufacturing steps, turns into an NRL material that can be used for many products, such as disposable gloves . NRL contains allergens that can cause immediate type I allergic reactions in people exposed to NRL‐containing products.…”

mentioning

confidence: 99%

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Decrease in the rate of sensitization and clinical allergy to natural rubber latex

et al. 2015

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Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 56%

mentioning

confidence: 99%

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Decrease in the rate of sensitization and clinical allergy to natural rubber latex

et al. 2015

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“…Additionally, in children with spina bifida also a high prevalence of latex sensitization (up to 72%) was observed. The milky sap of the rubber tree Hevea brasiliensis is the source for the production of commercial natural rubber latex (NRL) devices and represents also a source of potent allergenic proteins (Fig. ).…”

Section: The Allergen Sourcesmentioning

confidence: 99%

EAACI Molecular Allergology User's Guide

Matricardi

Kleine-Tebbe²,

Hoffmann

et al. 2016

Pediatric Allergy Immunology

724

870

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The availability of allergen molecules ('components') from several protein families has advanced our understanding of immunoglobulin E (IgE)-mediated responses and enabled 'component-resolved diagnosis' (CRD). The European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User's Guide (MAUG) provides comprehensive information on important allergens and describes the diagnostic options using CRD. Part A of the EAACI MAUG introduces allergen molecules, families, composition of extracts, databases, and diagnostic IgE, skin, and basophil tests. Singleplex and multiplex IgE assays with components improve both sensitivity for low-abundance allergens and analytical specificity; IgE to individual allergens can yield information on clinical risks and distinguish cross-reactivity from true primary sensitization. Part B discusses the clinical and molecular aspects of IgE-mediated allergies to foods (including nuts, seeds, legumes, fruits, vegetables, cereal grains, milk, egg, meat, fish, and shellfish), inhalants (pollen, mold spores, mites, and animal dander), and Hymenoptera venom. Diagnostic algorithms and short case histories provide useful information for the clinical workup of allergic individuals targeted for CRD. Part C covers protein families containing ubiquitous, highly cross-reactive panallergens from plant (lipid transfer proteins, polcalcins, PR-10, profilins) and animal sources (lipocalins, parvalbumins, serum albumins, tropomyosins) and explains their diagnostic and clinical utility. Part D lists 100 important allergen molecules. In conclusion, IgE-mediated reactions and allergic diseases, including allergic rhinoconjunctivitis, asthma, food reactions, and insect sting reactions, are discussed from a novel molecular perspective. The EAACI MAUG documents the rapid progression of molecular allergology from basic research to its integration into clinical practice, a quantum leap in the management of allergic patients.

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“…Sensitization to latex proteins is found in health care workers, in patients with atopic diathesis, and is especially common in patients with spina bifi da or urogenital malformations [ 52,53 ] . Sensitization to latex proteins is found in health care workers, in patients with atopic diathesis, and is especially common in patients with spina bifi da or urogenital malformations [ 52,53 ] .…”

Section: Latexmentioning

confidence: 99%

Pre‐ and perioperative aspects of dermatosurgery

Müller

Hübner

Thieme‐Ruffing

et al. 2017

J Deutsche Derma Gesell

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Die Dermatochirurgie nimmt hinsichtlich vieler Punkte eine Sonderstellung unter den operativen Fächern ein. Hierzu gehört in erster Linie die Tatsache, dass bis auf weni-ge Ausnahmen fast alle Eingriffe traditionell in Lokal-bzw. Regionalanästhesie und oft auch in räumlich-infrastruktureller Trennung von den großen Zentral-Operationssälen stattfinden können. Die peri-und postoperative Überwachung obliegt dabei dem der-matochirurgischen Operationsteam. Das sui generis kleinere OP-Team hat somit eine ganze Reihe perioperativer Notwendigkeiten zu beachten, um die sich in den "großen" chirurgischen Fächern eine Vielzahl verschiedener beteiligter Fachgruppen gemeinsam kümmern. Hierzu gehören neben Hygieneaspekten, Kenntnissen in der Überwachung der Patienten sowie dem Aspekt der surgical site infections auch Fragen zur postope-rativen Schmerztherapie sowie detailliertes pharmakologisches Wissen über die zur Anwendung kommenden Lokalanästhetika und das Handling der damit assoziierten toxischen und allergischen Reaktionen. Eine interdisziplinäre Zusammenarbeit und Verantwortung für den Patienten ist notwendig und erfordert die Erarbeitung und Um-setzung qualitätsorientierter und evidenzbasierter Handlungsanweisungen, die im der-matochirurgischen OP-Setting meist weit über das eigentliche Fach hinausgehen. Ziel dieses Weiterbildungsartikels soll die komprimierte Darstellung der genannten fach-übergreifenden Standpunkte bezüglich der wichtigsten perioperativen Aspekte sein. Summary Dermatosurgery occupies an exceptional position among all surgical disciplines. Above all, this includes the fact that, with very few exceptions, the vast majority of surgical interventions can be performed under local or regional anesthesia, usually in smaller procedure rooms that are spatially separated from larger operating suites. Thus, peri-and postinterventional patient monitoring is the responsibility of the dermatosurgeon and his team. Though inherently smaller, this team still has to observe numerous peri-operative requirements that-in larger surgical specialties-would be attended to by a host of various specialists working in concert. Said requirements include hygienic aspects , knowledge concerning pre-and intraoperative patient monitoring, managing surgical site infections, adequate postsurgical pain management, as well as detailed pharmacological knowledge with respect to common local anesthetics and the toxic and allergic reactions associated therewith. Not only does this require interdisciplinary collaboration and shared responsibility for the patient. It also necessitates the development and implementation of quality-oriented and evidence-based guidelines that, in the dermatosurgical setting, usually extend far beyond the scope of the specialty per

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The Latex Story

Cited by 32 publications

References 50 publications

Decrease in the rate of sensitization and clinical allergy to natural rubber latex

Decrease in the rate of sensitization and clinical allergy to natural rubber latex

EAACI Molecular Allergology User's Guide

Pre‐ and perioperative aspects of dermatosurgery

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