2011
DOI: 10.1016/j.jep.2011.03.059
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The latex obtained from Hancornia speciosa Gomes possesses anti-inflammatory activity

Abstract: Our results indicate that the latex obtained from Hancornia speciosa demonstrates significant anti-inflammatory activity through the inhibition of nitric oxide, PGE2, and cytokine production, thus confirming the popular use of this plant as an anti-inflammatory agent.

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Cited by 77 publications
(70 citation statements)
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References 33 publications
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“…In the case of H. speciosa, some scientific studies have showed the pharmacological potential of different parts of this plant. The extract obtained from the leaves has a hypotensive effect (Ferreira et al, 2007;Silva et al, 2011), the bark has anti-bactericidal activity (Moraes et al, 2008), and the latex has anti-inflammatory (Marinho et al, 2011) and angiogenic activities (Almeida et al, 2014). All these studies have been important to validating popular use of the mangabeira in diverse health practices.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In the case of H. speciosa, some scientific studies have showed the pharmacological potential of different parts of this plant. The extract obtained from the leaves has a hypotensive effect (Ferreira et al, 2007;Silva et al, 2011), the bark has anti-bactericidal activity (Moraes et al, 2008), and the latex has anti-inflammatory (Marinho et al, 2011) and angiogenic activities (Almeida et al, 2014). All these studies have been important to validating popular use of the mangabeira in diverse health practices.…”
Section: Discussionmentioning
confidence: 99%
“…In another study, Marinho et al (2011) evaluated the H. speciosa toxicity in mice after oral latex administration analyzing the following parameters: convulsion, hyperactivity, seduction, grooming, loss of righting reflex, increase and decrease in respiration, and food and water intake. The results showed that H. speciosa latex does not have any toxic effect in mice.…”
Section: Discussionmentioning
confidence: 99%
“…In a study in mice, the use of latex was associated with the inhibition of nitric acid and PGE2 formation and cytokinin production, indicating an anti-inflammatory activity (Marinho et al, 2011). The antimicrobial potential of mangabeira latex against different microorganisms, such as bacterium and fungi, has been demonstrated in studies with rabbits (Santos et al, 2007).…”
Section: Mangaba Latex: Technological and Pharmacological Propertiesmentioning
confidence: 98%
“…Coletânea bibliográfica sobre a mangabeira (Marinho et al 2011) e atividade angiogênica (Almeida et al 2014), bem como averiguaram se a atividade antifúngica atribuída ao látex é realmente oriunda deste, ou, se é oriunda de bactérias que se alojam neste componente vegetal (Silva et al 2011d). Ainda, um estudo avaliou as propriedades de um extrato hidroalcoólico da casca da espécie quanto à capacidade de prevenir e curar úlceras gástricas em roedores (Moraes et al 2008).…”
Section: Ciências Da Saúdeunclassified